9 Results for "

SIRT7

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "SIRT7" in MCE Product Catalog:

  • Isoforms Recommended:
6
6 Cited Publications
Cat. No.: HY-135899
CAS No.: 1807758-81-1
Purity:  98.81%
Target:  

Sirtuin Apoptosis

Research Areas:  

Cancer

SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway. .
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2
2 Cited Publications
Cat. No.: HY-N0912
CAS No.: 81720-08-3
Rehmannioside D is an orally active Sirt7 modulator. Rehmannioside D upregulates Sirt7 expression, inhibits the level of acetylated p53, and blocks the activation of the p53 signaling pathway. Rehmannioside D alleviates liver injury, inflammatory response, collagen deposition and hepatocyte apoptosis. Rehmannioside D is applicable to research related to liver fibrosis .
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Cat. No.: HY-RS12953
Research Areas:  

Others

SIRT7 Human Pre-designed siRNA Set A contains three designed siRNAs for SIRT7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12954
Research Areas:  

Others

Sirt7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sirt7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-159124
CAS No.: 3031072-69-9
Target:  

Sirtuin

Research Areas:  

Cancer

YZL-51N is a selective SIRT7 inhibitor with IC50 value of 12.71 μM. YZL-51N disrupts SIRT7 enzyme activity by occupying the NAD + binding pocket, thereby weakening DNA damage repair and inhibiting cancer cell survival. YZL-51N possesses anti-tumor activity and can be used in cancer research .
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Cat. No.: HY-RS12955
Research Areas:  

Others

Sirt7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sirt7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0912R
CAS No.: 81720-08-3
Rehmannioside D (Standard) is the analytical standard of Rehmannioside D (HY-N0912). This product is intended for research and analytical applications. Rehmannioside D is an orally active Sirt7 modulator. Rehmannioside D upregulates Sirt7 expression, inhibits the level of acetylated p53, and blocks the activation of the p53 signaling pathway. Rehmannioside D alleviates liver injury, inflammatory response, collagen deposition and hepatocyte apoptosis. Rehmannioside D is applicable to research related to liver fibrosis .
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Cat. No.: HY-156489
CAS No.: 2640673-56-7
Target:  

Sirtuin

Research Areas:  

Cancer

Epigenetic factor-IN-1 (40569Z) is a epigenetic factor inhibitor. Epigenetic factor-IN-1 has strong binding effect on SIRT7. Epigenetic factor-IN-1 can be used for liver cancer research .
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Cat. No.: HY-P87072
Synonyms: NAD dependent deacetylase SIRTuin 7 antibody; NAD dependent protein deacetylase SIRTuin 7 antibody; NAD-dependent protein deacetylase SIRTuin-7 antibody; Regulatory protein SIR2 homolog 7 antibody; Silent mating type information regulation 2 homolog antibody; Silent mating type information regulation 2 S.cerevisiae homolog 7 antibody; SIR2 L7 antibody; SIR2 like protein 7 antibody; Sir2 related protein type 7 antibody; SIR2, S.CEREVISIAE, HOMOLOG-LIKE 7 antibody

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP, ChIP

Reactivity:  

Human, Mouse, Rat

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