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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
SMS 1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "SMS 1" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-N8518
CAS No.: 63335-25-1
Category:
Metabolic Disease Phenols Polyphenols Myristicaceae Plants Myristica fragrans Houtt. Disease Research Fields
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3
3 Cited Publications
Target:
Research Areas:
SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM) .
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SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis .
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SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively. Anti-chronic inflammatory activity .
Cat. No.: HY-N8518R
CAS No.: 63335-25-1
Cat. No.: HY-102041R
CAS No.: 2098890-15-2
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Research Areas:
SMS2-IN-1 (Standard) is the analytical standard of SMS2-IN-1 (HY-102041). This product is intended for research and analytical applications. SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
