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SMS1-IN-1 

Cat. No.: HY-135642
Handling Instructions

SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis.

For research use only. We do not sell to patients.

SMS1-IN-1 Chemical Structure

SMS1-IN-1 Chemical Structure

CAS No. : 1807943-38-9

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Description

SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis[1].

IC50 & Target

IC50: 2.1 μM (SMS1)[1]

In Vitro

SMS1-IN-1 (2.5, 10 and 50 μM) has a dose-dependent inhibitory effect against SMS1, and is against SMS1 with an IC50 value of 2.1 μM[1].

Molecular Weight

503.41

Formula

C₂₃H₂₃BrN₂O₄S

CAS No.

1807943-38-9

SMILES

O=C(NCC1=CC=C(Br)C=C1)COC2=CC=C(S(=O)(NCCC3=CC=CC=C3)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

SMS1-IN-1OthersatherosclerosisSM biosyntheticInhibitorinhibitorinhibit

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