2 Results for "

SNARE complex

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SNARE complex" in MCE Product Catalog:

C18-Ceramide (d18:1/18:0)
C18-Ceramide (d18:1/18:0)
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Cat. No.: HY-100355
CAS No.: 2304-81-6
Purity:  99.95%
Synonyms: C18-Ceramide
Category:  

Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .
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DD04107
DD04107
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Cat. No.: HY-182539
CAS No.: 1202877-06-2
Target:  

CGRP Receptor

Research Areas:  

Others Neurological Disease

DD04107 is a neuronal exocytosis inhibitor with a rat Syt1-C2B domain binding Ka of 2.4 μM. DD04107 interferes with synaptobrevin-syntaxin-SNAP-25 complex formation and Syt1-SNARE complex interaction to block α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons. DD04107 blocks inflammatory ion channel recruitment to nociceptor plasma membranes. DD04107 can be used for the research of chronic inflammatory pain, neuropathic pain, osteosarcoma pain, chemotherapy-induced peripheral neuropathy, diabetic neuropathy, inflammatory pain .
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