Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
SORT1
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "SORT1" in MCE Product Catalog:
3
Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting) .
1
1 Cited Publications
Cat. No.: HY-W747072
CAS No.: 71781-33-4
Synonyms: 3-Sulfocholyl Taurine; TCA3S
Target:
Research Areas:
3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine; TCA3S) is a metabolite of the conjugated bile acid taurocholic acid. Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.
1
Cat. No.: HY-D1581
CAS No.: 878674-84-1
Target:
Research Areas:
BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis [1].
Cat. No.: HY-P991011
CAS No.: 2923556-87-8
Synonyms: AL101; GSK-4527226
Target:
Research Areas:
Cat. No.: HY-RS13575
Target:
Research Areas:
SORT1 Human Pre-designed siRNA Set A contains three designed siRNAs for SORT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27567
Target:
Research Areas:
Sort1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sort1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-132975
CAS No.: 2231405-64-2
PrDiAzK is a bifunctional amino acid. PrDiAzK can be site-selectively incorporated into proteins in both bacterial and mammalian cell culture. PrDiAzK can be used for proteome-wide incorporation via stochastic orthogonal recoding of translation (SORT) . PrDiAzK is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-RS21049
Target:
Research Areas:
Sort1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sort1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-159878
CAS No.: 3031580-91-0
Target:
Research Areas:
SORT1-IN-5 (compound 3) is a blood-brain barrier permeable SORT1 inhibitor. SORT1-IN-5 is an MSOH salt with limited oral bioavailability [1].
Cat. No.: HY-159868
CAS No.: 2806762-69-4
Target:
Research Areas:
SORT1-IN-1 (compound 2) is a SORT1 inhibitor [1].
Cat. No.: HY-159875
CAS No.: 2854233-44-4
Target:
Research Areas:
SORT1-IN-2 (compound 6) is a SORT1 inhibitor [1].
Cat. No.: HY-159876
CAS No.: 2915675-56-6
Target:
Research Areas:
SORT1-IN-3 (compound 5) is a blood-brain barrier permeable SORT1 inhibitor [1].
Cat. No.: HY-159877
CAS No.: 2915675-58-8
Target:
Research Areas:
SORT1-IN-4 (compound 6) is a blood-brain barrier permeable SORT1 inhibitor [1].
Cat. No.: HY-153687
CAS No.: 1008233-79-1
Target:
Research Areas:
SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases extracellular PGRN secretion in mammalian cell lines. SORT-PGRN interaction inhibitor 2 can be used for neurological disease research [1].
Cat. No.: HY-P705493
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SORTilin; SORT1; 100 kDa NT receptor; Glycoprotein 95; Gp95; Gp95LDLCQ6; Neurotensin receptor 3; NT3NTR3; Ntr3; SORTilin 1
Species:
Source:
Cat. No.: HY-P705494
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SORTilin; SORT1; 100 kDa NT receptor; Glycoprotein 95; Gp95; Gp95LDLCQ6; Neurotensin receptor 3; NT3NTR3; Ntr3; SORTilin 1
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
