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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
109 Results for "
SPACE peptide
" in MedChemExpress (MCE) Product Catalog:
Products (109)
109 Results for "SPACE peptide" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P0123
CAS No.: 1621717-95-0
Cat. No.: HY-P3669
CAS No.: 200427-88-9
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Cat. No.: HY-P4198
CAS No.: 2375600-56-7
Synonyms: Fmoc-Sar10
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Cat. No.: HY-P4076
CAS No.: 791642-10-9
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Cat. No.: HY-179477
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Fmoc-β-Ala-Asp(OMpe)-OH is a specialized amino acid derivative used in solid-phase peptide synthesis (SPPS). Fmoc-β-Ala-Asp(OMpe)-OH consists of a beta-alanine spacer linked to an aspartic acid residue, where the beta-carboxyl group is protected with a 3-methylpentyl ester (OMpe) to prevent aspartimide formation during synthesis. Fmoc-β-Ala-Asp(OMpe)-OH a useful building block for creating peptides that contain aspartic acid, as the OMpe group is designed to minimize unwanted side reactions .
Cat. No.: HY-W190842
CAS No.: 1127247-34-0
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m-PEG2-NHS ester is a PEG linker containing an NHS ester. The NHS ester of m-PEG2-NHS ester is used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. The hydrophilic PEG spacer effectively improves solubility in aqueous media. m-PEG2-NHS ester can be used in studies related to bioconjugation with ADC, proteins, peptides and other molecules .
Cat. No.: HY-120764
CAS No.: 1207481-21-7
PF-46396 is a potent HIV-1 inhibitor with an EC50 value of 0.206 µM. PF-46396 shows antiviral activity. PF-46396 inhibits the processing of capsid (CA)/spacer peptide 1 (SP1) (p25) Gag precursor proteins and blocks maturation of the viral core particle .
Cat. No.: HY-P5057B
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Cat. No.: HY-P10567
Cat. No.: HY-172513
CAS No.: 2183440-28-8
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Methyltetrazine-PEG11-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
Cat. No.: HY-W800723
CAS No.: 2698340-95-1
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Methyltetrazine-PEG2-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
Cat. No.: HY-P5350
CAS No.: 809281-07-0
Cat. No.: HY-P10306
Cat. No.: HY-P11731
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Cat. No.: HY-D3565
Cat. No.: HY-P11718
CAS No.: 1000977-62-7
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Cat. No.: HY-187415A
Synonyms: DOPE-PEG2000-Mal-Cys-TAASGVRSMH
DOPE provides a hydrophobic phospholipid anchor for membrane insertion, PEG2000 forms a hydrophilic spacer that enhances circulation stability, and the TAASGVRSMH peptide serves as a tumor-vasculature-homing ligand identified by in vivo phage display.
This conjugate can be used to functionalize liposomes and lipid nanoparticles for targeted drug delivery to tumor vasculature.
Cat. No.: HY-LD005
1.2 billion compounds
Cyclic peptide library have advantages such as high affinity, high selectivity, and suitability for targeting protein–protein interactions. Through DEL synthesis technology, the library size can achieve hundreds of millions. DEL cyclic peptide library have advantages like low cost andhigh screeing efficiency, making them valuable for discovering lead compounds against challenging drug targets.
This cyclic peptide library is constructed with unnatural amino acids as building block, synthesized through DNA-compatible chemical reactions. Each cyclic peptide consist of six amino acids and constrained conformations such as side-chain cross-linking, disulfide bonds, and macrocyclization. These cyclic peptides exhibit significantly improved stability and druggability compared with linear peptides, filling the gap between small molecules and macromolecular biologics. Each cyclic peptide is uniquely conjugated to a DNA barcode sequence for molecular identification and sequencing decoding.
MCE’s cyclic peptide library has8 independent sub-libraries, with a total molecular diversity of 1.2 billion. It is constructed via multi-round combinatorial assembly of building blocks and diverse cyclization strategies, facilitating the discovery of cyclic peptide leads for undruggable targets.
Cat. No.: HY-D3568
Cat. No.: HY-187245A
Synonyms: DSG-PEG2000-CSRNLIDC
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
