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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
ST2
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "ST2" in MCE Product Catalog:
3
Target:
Research Areas:
1
1 Cited Publications
Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction . (From patent WO2007078113A1, compound 39)
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Cat. No.: HY-168532
CAS No.: 3099811-61-4
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ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
Cat. No.: HY-P99729
CAS No.: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160
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Cat. No.: HY-155193
Purity: 99.77%
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XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNγ biomarkers in the graft versus host disease (GVHD) mice model .
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Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis .
Cat. No.: HY-P991633
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Cat. No.: HY-RS06725
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IL1RL1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL1RL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W338764
CAS No.: 23749-58-8
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AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research .
Cat. No.: HY-W060417
CAS No.: 1019158-02-1
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iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease [2].
Cat. No.: HY-RS29497
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GAL3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for GAL3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
GAL3ST2 siRNA-1: 5 nmol (HPLC)
GAL3ST2 siRNA-2: 5 nmol (HPLC)
GAL3ST2 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Components
GAL3ST2 siRNA-1: 5 nmol (HPLC)
GAL3ST2 siRNA-2: 5 nmol (HPLC)
GAL3ST2 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Cat. No.: HY-174607
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Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
Cat. No.: HY-P11298
CAS No.: 2120397-85-3
Research Areas:
Cat. No.: HY-P705138
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor-like 1; Protein ST2; DER4; ST2; T1
Cat. No.: HY-P705134
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor-like 1; Protein ST2; DER4; ST2; T1
Cat. No.: HY-RS06378
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HS3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06383
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HS6ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS6ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
