14 Results for "

Sennoside

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Sennoside" in MCE Product Catalog:

Sennoside
Sennoside
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Cat. No.: HY-N12281
CAS No.: 517-43-1
Category:  

Quinones Anthraquinones Leguminosae Extract Plants Senna alexandrina Milll

Target:  

Apoptosis MDM-2/p53 PAK Calcium Channel

Sennoside is an orally active apoptosis inducer and stimulant laxative, found in Senna (Cassia angustifolia). Sennoside induces overexpression of wild-type p53 and p21/WAF as part of pathways mediating colonic epithelial cell apoptosis. Sennoside stimulates colonic peristalsis, reverses net water, sodium, chloride absorption to secretion and enhances potassium and calcium secretion. Sennoside increases paracellular permeability to small molecules, accelerates colon transit and softens fecal pellets. Sennoside can be used for the research of constipation, melanosis coli, and colorectal cancer .
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Sennoside A
Sennoside A
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7 Publications Verification
Cat. No.: HY-N0365
CAS No.: 81-27-6
Category:  

Infection Quinones Anthraquinones Leguminosae Extract Plants Disease Research Fields Senna alexandrina Milll

Target:  

DNA/RNA Synthesis HIV

Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
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Sennoside B
Sennoside B
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3 Cited Publications
Cat. No.: HY-N0366
CAS No.: 128-57-4
Category:  

Quinones Anthraquinones Leguminosae Extract Plants Cassia angustifolia Disease Research Fields Cancer

Target:  

PDGFR

Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis .
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Sennoside C
Sennoside C
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1 Cited Publications
Cat. No.: HY-N1972
CAS No.: 37271-16-2
Category:  

Quinones Anthraquinones Other Diseases Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia Disease Research Fields

Target:  

Others

Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
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Rhein 8-O-β-D-Glucopyranoside
Rhein 8-O-β-D-Glucopyranoside
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1 Cited Publications
Cat. No.: HY-N6082
CAS No.: 34298-86-7
Category:  

Quinones Monophenols Rheum palmatum L. Anthraquinones Metabolic Disease Phenols Plants Disease Research Fields Polygonaceae Extract

Target:  

Apoptosis Bcl-2 Family Caspase TGF-beta/Smad Bacterial

Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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Sennoside D
Sennoside D
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Cat. No.: HY-N1973
CAS No.: 37271-17-3
Category:  

Quinones Anthraquinones Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia Disease Research Fields Inflammation/Immunology

Target:  

Others

Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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Sennoside A (Standard)
Sennoside A (Standard)
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Cat. No.: HY-N0365R
CAS No.: 81-27-6
Category:  

Infection Quinones Plants Disease Research Fields

Target:  

Reference Standards HIV

Sennoside A (Standard) is the analytical standard of Sennoside A. This product is intended for research and analytical applications. Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia) . Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication .
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Sennoside B (Standard)
Sennoside B (Standard)
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Cat. No.: HY-N0366R
CAS No.: 128-57-4
Category:  

Quinones Leguminosae Extract Plants Cassia angustifolia Disease Research Fields Cancer

Target:  

Reference Standards PDGFR

Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia) . Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway .
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Sennoside C (Standard)
Sennoside C (Standard)
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Cat. No.: HY-N1972R
CAS No.: 37271-16-2
Category:  

Quinones Anthraquinones Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia

Target:  

Reference Standards Others

Sennoside C (Standard) is the analytical standard of Sennoside C (HY-N1972). This product is intended for research and analytical applications. Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
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Sennoside D (Standard)
Sennoside D (Standard)
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Cat. No.: HY-N1973R
CAS No.: 37271-17-3
Category:  

Quinones Anthraquinones Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia

Target:  

Reference Standards Others

Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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Sennoside G
Sennoside G
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Cat. No.: HY-N21962
CAS No.: 66575-30-2
Synonyms: Sennoside A1
Category:  

Polysaccharides Leguminosae Extract Plants Senna alexandrina Milll Saccharides

Target:  

Others

Sennoside G (Sennoside A1) is a glycoside that is found in the leaves of Cassia angustifolia (senna leaves) .
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Rhein 8-O-β-D-Glucopyranoside (Standard)
Rhein 8-O-β-D-Glucopyranoside (Standard)
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Cat. No.: HY-N6082R
CAS No.: 34298-86-7
Category:  

Quinones Monophenols Rheum palmatum L. Anthraquinones Phenols Plants Polygonaceae Extract

Target:  

Reference Standards Apoptosis Bacterial Bcl-2 Family Caspase TGF-beta/Smad

Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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Senna extract
Senna extract
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Cat. No.: HY-N18652
CAS No.: 85187-05-9
Category:  

Extract

Target:  

Bacterial

Senna extract contains anthraquinone compounds, such as sennosides A and B, which have laxative properties. Sennosides in senna extract can stimulate colon muscles, promote intestinal peristalsis, and relieve constipation.
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Senna leaf extract
Senna leaf extract
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Cat. No.: HY-N18716
CAS No.: 85085-71-8
Category:  

Extract

Target:  

Others

Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.
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