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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
TAOK2
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "TAOK2" in MCE Product Catalog:
235
235 Cited Publications
Synonyms: Antibiotic AM-2282; STS; AM-2282
Cat. No.: HY-122232
CAS No.: 422281-45-6
SW083688 is a selective TAOK2 inhibitor with an IC50 of 1.3 μM. SW083688 increases the abundance of p62 protein, inhibits autophagosome maturation, and blocks Autophagic flux. SW083688 is applicable for the research of non-small cell lung cancer and pancreatic cancer [2].
Cat. No.: HY-15141R
CAS No.: 62996-74-1
Synonyms: Antibiotic AM-2282 (Standard); STS (Standard); AM-2282 (Standard)
Cat. No.: HY-RS14199
Target:
Research Areas:
TAOK2 Human Pre-designed siRNA Set A contains three designed siRNAs for TAOK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20110
Target:
Research Areas:
Taok2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Taok2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26614
Target:
Research Areas:
Taok2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Taok2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701641
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TAOK2; Prostate-Derived Sterile 20-Like Kinase 1; TAO Kinase 2; Kinase From Chicken Homolog C; Serine/Threonine-Protein Kinase TAO2; PSK1-BETA; MAP3K17; KIAA0881; HKFC-C; Tao2beta; PSK-1; TAO1; PSK1; TAO2; PSK; Prostate-Derived STE20-Like Kinase 1; Thousa
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181280
Target:
Research Areas:
VU6083859 is a blood-brain barrier-permeable TAOK1 inhibitor with an IC50 of 158 nM. VU6083859 selectively inhibits TAOK1, exhibits only weak or no activity against TAOK2 and TAOK3, and shows high selectivity for a variety of other kinases. VU6083859 is applicable to research related to neurodevelopmental disorders and tauopathies.
Cat. No.: HY-181281
Target:
Research Areas:
VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer .
Cat. No.: HY-181619
CAS No.: 3114565-22-6
Target:
Research Areas:
TAO Kinase-IN-3 is a potent pan-TAOK (Thousand-And-One Kinase) inhibitor that specifically binds to and inhibits the kinase activities of TAOK1, TAOK2 and TAOK3 with Kd values of <0.17 nM, 0.34 nM, and 0.17 nM, respectively. TAO Kinase-IN-3 can be used to study Alzheimer's disease, primary tauopathies and related syndromes. In addition, TAO Kinase-IN-3 is also widely used in research on the mechanisms of cancer cachexia and the muscle atrophy it induces .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
