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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
TGFBR2
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "TGFBR2" in MCE Product Catalog:
4
4 Cited Publications
Research Areas:
XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 induces apoptosis in hepatocellular carcinoma (HCC) cells and has antitumor effects .
2
2 Cited Publications
Research Areas:
TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295) .
1
1 Cited Publications
Cat. No.: HY-P700785
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2
1
Cat. No.: HY-RS14447
Target:
Research Areas:
TGFBR2 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFBR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14448
Target:
Research Areas:
Tgfbr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tgfbr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14449
Target:
Research Areas:
Tgfbr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tgfbr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-137063
CAS No.: 1409968-46-2
Target:
Research Areas:
(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs) .
Cat. No.: HY-174530
Target:
Research Areas:
Human TGFBR2 mRNA encodes the human transforming growth factor beta receptor 2 (TGFBR2) protein, a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. TGFBR2/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis.
Cat. No.: HY-P99963
CAS No.: 2387417-06-1
Synonyms: HS636
Target:
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Cat. No.: HY-100115R
CAS No.: 1784751-19-4
Target:
Research Areas:
TA-02 (Standard) is the analytical standard of TA-02 (HY-100115). This product is intended for research and analytical applications. TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295) .
Cat. No.: HY-P81131
Synonyms: TGF-beta receptor type-2; TGF beta R2; TGFBR2; AAT 3; AAT3; FAA 3; FAA3; HNPCC6; MFS 2; MFS2; RIIC; TAAD 2; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFB R2; TGFbeta RII; TGFBR 2; TGFR 2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II. TGF-βRⅡ; TGFβRⅡ; TGF βRⅡ; TGFβ RⅡ.
Cat. No.: HY-P73428
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
