23 Results for "

TGFBR2

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "TGFBR2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-100115
CAS No.: 1784751-19-4
Purity:  99.85%
TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295) .
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2
2 Cited Publications
Cat. No.: HY-P700785
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB2; Transforming Growth Factor, Beta 2; Transforming Growth Factor Beta 2; BSC-1 Cell Growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor Factor; TGF-Beta2; Transforming Growth Factor Beta-2 Proprotein; Polyergin; Prepro-Transforming Growth Factor
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78524
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kinase; TBR-Ii; TGF-Beta Receptor Type IIB; TGFR-2; TGF-Beta Receptor Type II; TBRII; TGFbeta-RII; Transforming Growth Factor, Beta Receptor II (70/80kDa); LDS1B; Transforming Growth Factor-Beta Receptor Type II; LDS2B; Transforming Growth Factor Beta Receptor II; TAAD2; TbetaR-II; AAT3; Transforming Growth Factor, Beta Receptor II Epsilon; FAA3; Transforming Growth Factor, Beta Receptor II Alpha; LDS2; Transforming Growth Factor, Beta Receptor II Delta; RIIC; Transforming Growth Factor Beta Receptor 2; Transforming Growth Factor Beta Receptor Type IIC
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-RS14447
Research Areas:  

Others

TGFBR2 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFBR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14448
Research Areas:  

Others

Tgfbr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tgfbr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14449
Research Areas:  

Others

Tgfbr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tgfbr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-137063
CAS No.: 1409968-46-2
Research Areas:  

Cardiovascular Disease

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs) .
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Cat. No.: HY-174530
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human TGFBR2 mRNA encodes the human transforming growth factor beta receptor 2 (TGFBR2) protein, a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. TGFBR2/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis.
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Cat. No.: HY-P99963
CAS No.: 2387417-06-1
Synonyms: HS636

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1. Sudubrilimab is fused at the C terminus of the heavy chain to a TGF-β1 receptor Ⅱ ectodomain (TGFBR2-ECD), and which can sequester the PD-1/PD-L1 pathway and TGF-β bioactivity in the immunosuppressive tumor microenvironment .
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Cat. No.: HY-100115R
CAS No.: 1784751-19-4
TA-02 (Standard) is the analytical standard of TA-02 (HY-100115). This product is intended for research and analytical applications. TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295) .
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Cat. No.: HY-P86481
Synonyms: TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7427
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P7428
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78800
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78801
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P7426
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78215
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73430
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P704919
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77229
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta Receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kin
Species:  
Rhesus Macaque
Source:  
HEK293
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