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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
TIPARP
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "TIPARP" in MCE Product Catalog:
Cat. No.: HY-RS14546
Target:
Research Areas:
TIPARP Human Pre-designed siRNA Set A contains three designed siRNAs for TIPARP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14547
Target:
Research Areas:
Tiparp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tiparp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14548
Target:
Research Areas:
Tiparp Rat Pre-designed siRNA Set A contains three designed siRNAs for Tiparp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181027
CAS No.: 3106183-96-1
TIPARP-IN-1 (Compound 15) is a selective PARP7 (TIPARP) (2,3,7,8-Tetrachlorodiben-zo-p-dioxin(TCDD)-inducible PARP) inhibitor with an IC50 of 2.15 nM. TIPARP-IN-1 can restore IFN signaling pathway in tumors by inhibiting TIPARP. TIPARP-IN-1 selectively activates the anti-tumor immune response in the tumor microenvironment and avoids the production of systemic cytokines. TIPARP-IN-1 can be used for research of head and neck squamous cell carcinoma .
Cat. No.: HY-181629A
Research Areas:
ZSTK3744 is an aryl hydrocarbon receptor (AhR) agonist. ZSTK3744 directly binds to AhR, upregulates the expression of AhR target genes including CYP1A1, CYP1B1 and TIPARP, and mediates cell growth inhibitory activity in triple-negative breast cancer cells. ZSTK3744 induces apoptosis in triple-negative breast cancer cells. ZSTK3744 exhibits anti-tumor activity and can be used in the research of chemoresistant triple-negative breast cancer .
Cat. No.: HY-181629
CAS No.: 3106975-38-3
Research Areas:
ZSTK3744 free base is an aryl hydrocarbon receptor (AhR) agonist. ZSTK3744 free base directly binds to AhR, upregulates the expression of AhR target genes including CYP1A1, CYP1B1 and TIPARP, and mediates cell growth inhibitory activity in triple-negative breast cancer cells. ZSTK3744 free base induces apoptosis in triple-negative breast cancer cells. ZSTK3744 free base exhibits anti-tumor activity and can be used in the research of chemoresistant triple-negative breast cancer .
Cat. No.: HY-P703622
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TIPARP; PARP-1; TCDD Inducible Poly(ADP-Ribose) Polymerase; DDF1; ARTD14; RM1; PARP7; TCDD-Inducible Poly(ADP-Ribose) Polymerase, Isoform CRA_b; PARP-7; TCDD-Inducible Poly(ADP-Ribose) Polymerase, Isoform CRA_c; PART14; TCDD-Inducible Poly [ADP-Ribose] Po
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
