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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
TOR
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "TOR" in MCE Product Catalog:
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5 Cited Publications
Cat. No.: HY-N2031
CAS No.: 62499-28-9
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3 Cited Publications
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BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer .
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-Ceramide; Cer d18:1/22:0
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C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
Cat. No.: HY-124089
CAS No.: 109001-03-8
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Eicosapentaenoyl ethanolamide, an omega-3 fatty acid, is one of N-acylethanolamines (NAEs). Eicosapentaenoyl ethanolamide is cannabinoid CB1/CB2 receptor agonist. Eicosapentaenoyl ethanolamide acts as a metabolic signal. Eicosapentaenoyl ethanolamide inhibits dietary restriction (DR)-induced lifespan extension in wild type animals and suppresses lifespan extension in a TOR pathway mutant .
Cat. No.: HY-RS12132
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RORC Human Pre-designed siRNA Set A contains three designed siRNAs for RORC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-145281
CAS No.: 2376137-31-2
MS98 is a AKT PROTAC degrader with a DC50 of 78 nM in BT474 cells. MS98 binds to purified AKT1, AKT2 and AKT3 isoforms with Kd values of 4 nM, 140 nM and 8 nM, respectively. MS98 recruits the VHL E3 ligase to induce polyubiquitination and proteasomal degradation of AKT. MS98 inhibits downstream signal transduction of the PI3K/AKT/m-TOR pathway. MS98 suppresses cancer cell proliferation. MS98 can be used for the research of prostate cancer and breast cancer .
Cat. No.: HY-124114
CAS No.: 110503-62-3
Synonyms: 4-OH-TOR
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4-Hydroxytoremifene (4-OH-TOR) is an estrogen receptor antagonist that blocks the uterus's ability to absorb estradiol .
Cat. No.: HY-N0022R
CAS No.: 61303-13-7
Synonyms: Isoverbascoside (Standard)
Cat. No.: HY-RS14903
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TOR1A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14906
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TOR3A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14907
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TOR4A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14904
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TOR1AIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1AIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14905
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TOR1AIP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1AIP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12133
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Rorc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rorc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N2031R
CAS No.: 62499-28-9
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Cat. No.: HY-162363
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MD6a is a melatonin derivative with inhibitroy activity towards PARP-1, which maintains proteins hemostasis and improves mitochondrial function through TOR/HSF-1 signaling. MD6a a neuroprotective effect .
Cat. No.: HY-19262
CAS No.: 156756-10-4
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TAK-218 is a promising candidate as an agent tor central nervous system trauma and ischemia. TAK-218 exhibits potent scavenging activity and antioxidative activity. TAK-218 also inhibits dopamine release .
Cat. No.: HY-D3415
CAS No.: 3030070-69-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
