11 Results for "

Thioperamide

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Thioperamide" in MCE Product Catalog:

3
3 Cited Publications
Referencia número: HY-12206
No. CAS: 106243-16-7
Pureza:  99.91%
Synonyms: MR-12842
Target:  

Histamine Receptor

Áreas de investigación:  

Neurological Disease

Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [ 3H]histamine release. Thioperamide inhibits [ 3H]histamine synthesis with a Ki of 31 nM .
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3
3 Cited Publications
Referencia número: HY-12206A
No. CAS: 148440-81-7
Pureza:  98.26%
Synonyms: MR-12842 maleate
Target:  

Histamine Receptor

Áreas de investigación:  

Neurological Disease

Thioperamide maleate (MR-12842 maleate) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [ 3H]histamine release. Thioperamide maleate inhibits [ 3H]histamine synthesis with a Ki of 31 nM .
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1
1 Cited Publications
Referencia número: HY-P1103
No. CAS: 1030384-98-5
Target:  

CXCR

Áreas de investigación:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Referencia número: HY-P4070
No. CAS: 1188379-43-2
Target:  

Insulin Receptor

Áreas de investigación:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Referencia número: HY-P1103A
Target:  

CXCR

Áreas de investigación:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Referencia número: HY-P11293
No. CAS: 1309855-53-5
Target:  

Melanocortin Receptor

Áreas de investigación:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
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Referencia número: HY-P4757
No. CAS: 108081-77-2
Target:  

Parasite

Áreas de investigación:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Referencia número: HY-P1321
No. CAS: 158859-98-4
Synonyms: 1229U91; GW1229
Áreas de investigación:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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Referencia número: HY-107556
No. CAS: 639089-06-8
Target:  

Histamine Receptor

Áreas de investigación:  

Neurological Disease

VUF 5681 dihydrobromide is a neutral antagonist of histamine H3 receptor. VUF 5681 dihydrobromide also has partial agonist function of H3 receptor. VUF 5681 dihydrobromide blocks the effects of Thioperamide (HY-12206). VUF 5681 dihydrobromide is used in central nervous system disease research .
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Referencia número: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Áreas de investigación:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Referencia número: HY-P11480
No. CAS: 3105660-96-3
Target:  

Trk Receptor

Áreas de investigación:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
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