2. Search Result
Search Result
Results for "

USP25

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117370
    USP25/28 inhibitor AZ1
    5+ Cited Publications

    AZ1

    		 Deubiquitinase Cancer
    USP25/28 inhibitor AZ1 (AZ1) is an orally active, selective, noncompetitive, dual ubiquitin specific protease (USP) 25/28 inhibitor with IC50s of 0.7 μM and 0.6 μM, respectively. USP25/28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model .
    USP25/28 inhibitor AZ1
  • HY-138698
    FT206
    1 Publications Verification

    		 Deubiquitinase Cancer
    FT206 is the inhibitor for ubiquitin-specific protease that inhibits USP28 and USP25 with IC50s of 0.15 μM and 1.01 μM .
    FT206
  • HY-153996
    CT1113

    		Deubiquitinase Apoptosis Bcr-Abl STAT c-Myc Cancer
    CT1113 is a selective, orally active USP25/USP28 inhibitor. CT1113 inhibits cancer cell proliferation, induces apoptosis, and causes G2/S phase cell cycle arrest. CT1113 reduces the levels of total BCR-ABL1, phosphorylated BCR-ABL1, total STAT5, and phosphorylated STAT5, but does not alter the mRNA level of BCR-ABL1. CT1113 is applicable to research related to pancreatic cancer, colon cancer, and acute leukemia .
    CT1113
  • HY-RS15535
    USP25 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    USP25 Human Pre-designed siRNA Set A contains three designed siRNAs for USP25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    USP25 Human Pre-designed siRNA Set A
    USP25 Human Pre-designed siRNA Set A
  • HY-RS23599
    Usp25 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Usp25 Rat Pre-designed siRNA Set A contains three designed siRNAs for Usp25 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Usp25 Rat Pre-designed siRNA Set A
    Usp25 Rat Pre-designed siRNA Set A
  • HY-RS17150
    Usp25 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Usp25 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Usp25 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Usp25 Mouse Pre-designed siRNA Set A
    Usp25 Mouse Pre-designed siRNA Set A
  • HY-122686
    USP25/28-IN-2

    		Deubiquitinase Apoptosis c-Myc Cancer
    USP25/28-IN-2 is a selectivity dual USP25/28 inhibitor with IC50 values of 0.88 and 1.1 μM, respectively. USP25/28-IN-2 modulates USP25 and USP28 activity to affect downstream pathways, modulates c-Myc oncoprotein total levels and half-life, induces apoptosis, reduces cell viability. USP25/28-IN-2 can be used for the research of colorectal carcinoma, colorectal adenocarcinoma .
    USP25/28-IN-2
  • HY-183604
    T-10531

    		Deubiquitinase Cancer
    T-10531 is a selective USP25/USP28 inhibitor. T-10531 exhibits an IC50 of 0.03 μM and a Kd of 0.2 μM against human USP25, as well as an IC50 of 0.12 μM and a Kd of 0.06 μM against human USP28. T-10531 inhibits USP25/USP28 activity and induces the degradation of USP25 via the proteasomal pathway, without inhibiting other deubiquitinases. T-10531 can be used in the research of squamous cell carcinoma, colorectal cancer, gastric cancer, triple-negative breast cancer and pancreatic cancer .
    T-10531

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: