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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Uncharged
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Uncharged" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: CFTR Inhibitor
PPQ-102 (CFTR Inhibitor) is a reversible CFTR inhibitor that completely inhibits CFTR chloride currents (IC50 ~90 nM). PPQ-102 is not affected by membrane potential-dependent cell allocation or blocking efficiency (uncharged at physiological pH) and effectively prevents cyst enlargement in polycystic kidney disease .
Synonyms: Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
Research Areas:
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .
Cat. No.: HY-W278021
CAS No.: 439858-28-3
BTA-1 is an uncharged derivative of thioflavin-T. BTA-1 has a high affinity for Aβ fibrils and shows very good brain penetration and clearance .
Target:
ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
Cat. No.: HY-174367
CAS No.: 923865-06-9
RUNX1/ETO-IN-1 is a RUNX1-ETO oncogenic fusion protein inhibitor that specifically targets the NHR2 oligomerization domain. RUNX1/ETO-IN-1 directly interacts with the NHR2 (KD,app = 39 μM). RUNX1/ETO-IN-1 exhibits anti-leukemic activity by inducing apoptosis and promoting differentiation in RUNX1/ETO-translocated AML cells. RUNX1/ETO-IN-1 remains essentially uncharged at physiological pH, demonstrating superior membrane permeability.
Cat. No.: HY-W726893
CAS No.: 652966-03-5
Cat. No.: HY-136564
Target:
Research Areas:
DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function .
Cat. No.: HY-136564A
Target:
Research Areas:
DAD is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD is a third-generation photoswitch that responds to visible light. DAD has the potential for restoring visual function .
Cat. No.: HY-151035
CAS No.: 95856-73-8
Synonyms: BTA-1-CH3
Research Areas:
BTA-1_b (BTA-1-CH3) is a structural analog of BTA-1 (HY-W278021). BTA-1 is an uncharged derivative of Thioflavin-T. It exhibits high affinity for Aβ fibrils and demonstrates excellent brain penetration and clearance capabilities.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
