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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Vildagliptin
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Vildagliptin" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: LAF237; NVP-LAF 237
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Research Areas:
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
Cat. No.: HY-14291R
CAS No.: 274901-16-5
Synonyms: LAF237 (Standard); NVP-LAF 237 (Standard)
Research Areas:
Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
Cat. No.: HY-14291S1
CAS No.: 1133208-42-0
Synonyms: LAF237-d7; NVP-LAF 237-d7
Cat. No.: HY-14291S
CAS No.: 1217546-82-1
Synonyms: LAF237-d3; NVP-LAF 237-d3
Cat. No.: HY-14291A
CAS No.: 2133364-01-7
Synonyms: LAF237 dihydrate; NVP-LAF 237 dihydrate
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Research Areas:
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability and potent antihyperglycemic activity .
Cat. No.: HY-14291S2
CAS No.: 1044741-01-6
Synonyms: LAF237-13C5,15N; NVP-LAF 237-13C5,15N
Cat. No.: HY-W015329
CAS No.: 702-82-9
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Research Areas:
3-Amino-1-adamantanol is an intermediate. 3-Amino-1-adamantanol can be used to synthesize compounds such as Vildagliptin (HY-14291) .
Cat. No.: HY-G0024A
CAS No.: 565453-41-0
Synonyms: Vildagliptin carboxy acid metabolite TFA
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Vildagliptin carboxylic acid metabolite (M20.7) TFA is a potent P450 enzyme activity inhibitor .
Cat. No.: HY-14291S5
Synonyms: LAF237-d6 ; NVP-LAF 237-d6
Cat. No.: HY-14291B
CAS No.: 1036959-27-9
Synonyms: (2R)-LAF237; (2R)-NVP-LAF 237
Target:
Research Areas:
(2R)-Vildagliptin is the isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
Cat. No.: HY-G0024
CAS No.: 565453-40-9
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Research Areas:
Vildagliptin impurity 1 is an impurity of Vildagliptin (HY-14291).
Cat. No.: HY-Z1750
CAS No.: 214398-99-9
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Vildagliptin impurity 24 is an impurity of Vildagliptin (HY-14291).
Cat. No.: HY-139792
CAS No.: 1177460-72-8
Synonyms: SHR117887
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Research Areas:
Besigliptin tosylate (SHR117887) is a DPP-4 inhibitor with activity to improve metabolic control and β-cell function. Besigliptin tosylate can effectively reduce serum DPP-4 activity and improve oral glucose tolerance. Besigliptin tosylate significantly reduces fasting blood glucose levels and improves lipid profiles in a diabetic mouse model. The effect of besigliptin tosylate is comparable to that of the known compound vildagliptin (HY-14291) at the same concentration. Besigliptin tosylate increases insulin staining of pancreatic islet cells in chronic administration, indicating improved β-cell function .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
