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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
XOR
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "XOR" in MCE Product Catalog:
8
Target:
Research Areas:
Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment .
Cat. No.: HY-151975
CAS No.: 1026652-90-3
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Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia .
Cat. No.: HY-151973
CAS No.: 651769-78-7
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Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia .
Cat. No.: HY-W075315
CAS No.: 4329-78-6
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Xanthine oxidoreductase-IN-6 (Compound 4) is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 170 nM. Xanthine oxidoreductase-IN-6 can block the final step of uric acid biosynthesis and lower serum uric acid levels. Xanthine oxidoreductase-IN-6 also shows Cytochrome P450 3A4 (CYP3A4) inhibitory activity. Xanthine oxidoreductase-IN-6 can be used for the research of hyperuricemia .
Cat. No.: HY-161523
CAS No.: 2810137-86-9
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XOR/URAT1-IN-1 (Compound II15) is a dual inhibitor for xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), with IC50 of 6 nM and 12.9 μM. XOR/URAT1-IN-1 lowers the levels of uric acid in Potassium oxonate (HY-17511)/Hypoxanthine (HY-N0091)-induced acute hyperuricemia mouse model .
Cat. No.: HY-162882
CAS No.: 2482713-67-5
Research Areas:
CC15009 is a xanthine oxidoreductase (XOR) inhibitor, with an IC50 value of 0.237 nM. CC15009 can inhibit the oxidative subtype of XOR, thereby reducing the production of the byproduct ROS and exhibiting antioxidant activity. CC15009 has demonstrated a good dose-dependent uric acid-lowering effect in two different mouse models of hyperuricemia induced by XOR substrates .
Cat. No.: HY-146297
CAS No.: 2396612-45-4
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Xanthine oxidoreductase-IN-2 (Compound IVa) is a xanthine oxidoreductase (XOR) inhibitor with the IC50 of 7.2 nM. Xanthine oxidoreductase-IN-2 shows hypouricemic effects in mice .
Cat. No.: HY-14874R
CAS No.: 577778-58-6
Synonyms: FYX-051 (Standard)
Research Areas:
Topiroxostat (Standard) is the analytical standard of Topiroxostat. This product is intended for research and analytical applications. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment .
Synonyms: Y-700; Piraxostat
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Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase (XOR) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved .
Cat. No.: HY-RS15871
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Xdh Rat Pre-designed siRNA Set A contains three designed siRNAs for Xdh gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-151974
CAS No.: 1026587-58-5
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Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia .
Cat. No.: HY-RS15869
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XDH Human Pre-designed siRNA Set A contains three designed siRNAs for XDH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-146296
CAS No.: 2396612-00-1
Target:
Research Areas:
The compound is a xanthine oxidoreductase (XOR) inhibitor with high inhibitory concentration, and the value of ic50 is 7.0 nm.
Cat. No.: HY-RS15870
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Research Areas:
Xdh Mouse Pre-designed siRNA Set A contains three designed siRNAs for Xdh gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-14874S
CAS No.: 2732868-49-2
Synonyms: FYX-051-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
