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Results for "

acetoxymethyl (AM) ester

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Calcium Channel (1) Fluorescent Dye (10) Histone Acetyltransferase (1) Mitosis (1) Potassium Channel (1)
By Research Areas:	Cancer (1) Metabolic Disease (2) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Targets Recommended: CETP Carboxylesterase (CES) Hormone-Sensitive Lipase (HSL)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0041

Calcein-AM Maximum Cited Publications 83 Publications Verification Calcein acetoxymethyl ester	Fluorescent Dye	Cancer
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .

HY-101897

Fura-2 AM 5+ Cited Publications Fura-2 acetoxymethyl ester	Fluorescent Dye	Others
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca ²⁺ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.

HY-D0973

EGTA-AM 5+ Cited Publications EGTA acetoxymethyl ester	Biochemical Assay Reagents	Neurological Disease
EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca ²⁺ chelator with slow chelating dynamics.

HY-101898

Indo-1 AM 1 Publications Verification Indo-1 acetoxymethyl ester	Fluorescent Dye	Others
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .

HY-D1631

Calcium Green-5N AM	Fluorescent Dye Calcium Channel	Neurological Disease
Calcium Green-5N AM is a Ca ²⁺-sensitive fluorescent probe (K_d = 14 μM). Calcium Green-5N AM shows enhanced fluorescence intensity upon binding to Ca ²⁺, and it can monitor free Ca ²⁺ in neurons .

HY-D1746

EDTA-AM 2 Publications Verification EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester	Biochemical Assay Reagents Mitosis	Others
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .

HY-141894

5-Ph-IAA-AM 2 Publications Verification	Histone Acetyltransferase	Metabolic Disease
5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .

HY-158741

IPG-2 AM APG-2 acetoxymethyl ester	Fluorescent Dye Potassium Channel	Others
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .

HY-158746

Fluo-2 AM Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity	Fluorescent Dye	Others
Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration .

HY-101902

Quin-2AM Quin-2 acetoxymethyl ester	Fluorescent Dye	Others
Quin-2AM is a fluorecent Ca ²⁺ chelator, with high affinity for calcium. Quin-2AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .

HY-130575

Fura-FF AM	Fluorescent Dye	Others
Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.

HY-DY1101

Fura-2 AM (solution) Fura-2 acetoxymethyl ester (solution)	Fluorescent Dye	Others
Fura-2 AM (solution) (Fura-2 Acetoxymethyl ester (solution)) is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca ²⁺ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells. Solvent and concentration: DMSO: 1 mM

HY-W783351

CS790AM Coppersensor 790 acetoxymethyl ester	Fluorescent Dye	Metabolic Disease
CS790AM (Coppersensor 790 acetoxymethyl ester) is a cell-permeable, Cu ⁺-targeted near-infrared fluorescent probe (λ_abs=760 nm, λ_em=790 nm) applicable to live cells. CS790AM can cross lipophilic cell membranes, and is converted into negatively charged CS790 under the action of intracellular esterases to be retained, thus enabling highly sensitive, reversible "turn-on" detection of labile Cu ⁺ pools in live cells and mice. CS790AM possesses excellent biocompatibility and selectivity, avoids interference from other metal ions, shows no obvious toxicity, and can be rapidly cleared. CS790AM allows long-term longitudinal monitoring of individual mice, visualizes copper levels in internal organs and isolated livers, and effectively evaluates abnormal copper accumulation in Wilson's disease models (Atp7b ^-/-) as well as dynamic changes after chelator treatment. CS790AM can be used for research on Wilson's disease and related copper metabolic disorders .

Cat. No.	Product Name	Type

HY-D0041

Calcein-AM Maximum Cited Publications 83 Publications Verification Calcein acetoxymethyl ester	Fluorescent Dyes
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .

Calcein-AM

Maximum Cited Publications

83 Publications Verification

Calcein acetoxymethyl ester

Fluorescent Dyes

Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .

HY-101897

Fura-2 AM 5+ Cited Publications Fura-2 acetoxymethyl ester	Fluorescent Dyes
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca ²⁺ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.

HY-101898

Indo-1 AM 1 Publications Verification Indo-1 acetoxymethyl ester	Fluorescent Dyes
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .

Indo-1 AM

1 Publications Verification

Indo-1 acetoxymethyl ester

Fluorescent Dyes

Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .

HY-D1631

Calcium Green-5N AM	Fluorescent Dyes
Calcium Green-5N AM is a Ca ²⁺-sensitive fluorescent probe (K_d = 14 μM). Calcium Green-5N AM shows enhanced fluorescence intensity upon binding to Ca ²⁺, and it can monitor free Ca ²⁺ in neurons .

HY-D1746

EDTA-AM 2 Publications Verification EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester	Fluorescent Dyes
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .

EDTA-AM

2 Publications Verification

EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester

Fluorescent Dyes

EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .

HY-158741

IPG-2 AM APG-2 acetoxymethyl ester	Fluorescent Dyes
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .

IPG-2 AM

APG-2 acetoxymethyl ester

Fluorescent Dyes

IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .

HY-158746

Fluo-2 AM Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity	Fluorescent Dyes
Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration .

HY-101902

Quin-2AM Quin-2 acetoxymethyl ester	Fluorescent Dyes
Quin-2AM is a fluorecent Ca ²⁺ chelator, with high affinity for calcium. Quin-2AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .

HY-130575

Fura-FF AM	Fluorescent Dyes
Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.

HY-DY1101

Fura-2 AM (solution) Fura-2 acetoxymethyl ester (solution)	Fluorescent Dyes
Fura-2 AM (solution) (Fura-2 Acetoxymethyl ester (solution)) is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca ²⁺ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells. Solvent and concentration: DMSO: 1 mM

Cat. No.	Product Name	Type

HY-D0973

EGTA-AM 5+ Cited Publications EGTA acetoxymethyl ester	Biochemical Assay Reagents
EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca ²⁺ chelator with slow chelating dynamics.

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