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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
acetoxymethyl (AM) ester
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "acetoxymethyl (AM) ester" in MCE Product Catalog:
90
90 Publications Verification
Cat. No.: HY-D0041
CAS No.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
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9
9 Cited Publications
Synonyms: Fura-2 acetoxymethyl ester
2
2 Cited Publications
Cat. No.: HY-D1746
CAS No.: 162303-59-5
Synonyms: EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
2
2 Cited Publications
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5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .
1
1 Cited Publications
Synonyms: Indo-1 acetoxymethyl ester
1
1 Cited Publications
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Calcein Blue AM is a cell staining agent. Calcein Blue AM serves as a substrate for intracellular esterases, which hydrolyze its acetoxymethyl (AM) ester group to convert the non-fluorescent reagent into fluorescent Calcein Blue. Calcein Blue AM passively penetrates the plasma membrane of both live and dead cells; it is converted into a polar fluorescent product and retained in the cytoplasm of live cells, whereas dead cells cannot retain the dye. Calcein Blue AM exhibits significant dye leakage, and its fluorescence intensity gradually decreases over time. Calcein Blue AM can be used for endpoint-based cell viability assays and short-term cell tracking experiments with a duration of no more than 4 hours.
Cat. No.: HY-D1631
CAS No.: 216699-33-1
Cat. No.: HY-158741
CAS No.: 1369302-24-8
Synonyms: APG-2 acetoxymethyl ester
Cat. No.: HY-158746
CAS No.: 1070771-36-6
Synonyms: Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity
Cat. No.: HY-101902
CAS No.: 83104-85-2
Synonyms: Quin-2 acetoxymethyl ester
Cat. No.: HY-DY1101
CAS No.: 108964-32-5
Synonyms: Fura-2 acetoxymethyl ester (solution)
Solvent and concentration: DMSO: 1 mM
Cat. No.: HY-W783351
CAS No.: 1416808-87-1
Synonyms: Coppersensor 790 acetoxymethyl ester
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Research Areas:
CS790AM (Coppersensor 790 acetoxymethyl ester) is a cell-permeable, Cu +-targeted near-infrared fluorescent probe (λabs=760 nm, λem=790 nm) applicable to live cells. CS790AM can cross lipophilic cell membranes, and is converted into negatively charged CS790 under the action of intracellular esterases to be retained, thus enabling highly sensitive, reversible "turn-on" detection of labile Cu + pools in live cells and mice. CS790AM possesses excellent biocompatibility and selectivity, avoids interference from other metal ions, shows no obvious toxicity, and can be rapidly cleared. CS790AM allows long-term longitudinal monitoring of individual mice, visualizes copper levels in internal organs and isolated livers, and effectively evaluates abnormal copper accumulation in Wilson's disease models (Atp7b -/-) as well as dynamic changes after chelator treatment. CS790AM can be used for research on Wilson's disease and related copper metabolic disorders .
Cat. No.: HY-D3074
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Research Areas:
TCM-4COOH is an AIE-active fluorescent probe for calcium ions. TCM-4COOH relies on aggregation-induced emission activity, and its carboxyl chelating group can bind to Ca 2+ and Mg 2+ to form insoluble aggregates, triggering fluorescence enhancement via restricting intramolecular motion (Ex/Em = 477/603 nm). TCM-4COOH shows pH independence in physiological environments (pH 4-9), can be strongly activated at Ca 2+ concentrations ranging from low nM to mM, and has a stronger binding ability to Ca 2+ than to Mg 2+. TCM-4COOH, as its acetoxymethyl ester derivative TCM-AM, can penetrate cell membranes for intracellular detection. TCM-4COOH can be used for imaging of cellular calcium overload, detection of bone microcracks, and studies related to calcium-rich biological environments .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
