13 Results for "

albinism

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "albinism" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0607
CAS No.: 104206-65-7
Synonyms: NTBC; Nitisone; SC0735
Target:  

HPPD

Research Areas:  

Metabolic Disease

Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism .
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1
1 Cited Publications
Cat. No.: HY-N0321
CAS No.: 67879-58-7
Synonyms: trans-Caftaric acid
Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities .
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Cat. No.: HY-W040194
CAS No.: 81777-89-1
Research Areas:  

Metabolic Disease

Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity .
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Cat. No.: HY-B0607R
CAS No.: 104206-65-7
Synonyms: NTBC (Standard); Nitisone (Standard); SC0735 (Standard)
Research Areas:  

Metabolic Disease

Nitisinone (Standard) is the analytical standard of Nitisinone. This product is intended for research and analytical applications. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism .
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Cat. No.: HY-B0607S
Synonyms: NTBC-d3; Nitisone-d3; SC0735-d3
Nitisinone-d3 (NTBC-d3) is deuterium labeled Nitisinone. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism .
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Cat. No.: HY-W777526
CAS No.: 1246815-63-3
Nitisinone- 13C6 is a 13C-labeled Nitisinone (HY-B0607). Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism .
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Cat. No.: HY-116653
CAS No.: 96525-23-4
Target:  

Herbicide

Research Areas:  

Others

Flurtamone is a herbicide that interferes with carotenoid biosynthesis by inhibiting phytoene desaturase, blocking the conversion of phytoene to ζ-carotene. Flurtamone can cause the accumulation of phytoene, leading to photooxidative destruction of chlorophyll and plant albinism . Flurtamone comprises a pair of chiral enantiomers, R-flurtamone and S-flurtamone, with R-flurtamone exhibiting significantly stronger herbicidal activity against target weeds. Flurtamone is toxic to Selenastrum capricornutum. Flurtamone can control broadleaf weeds and grass weeds as well as various weeds, and can be used in herbicide-related research .
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Cat. No.: HY-W040194R
CAS No.: 81777-89-1
Research Areas:  

Metabolic Disease

Clomazone (Standard) is the analytical standard of Clomazone (HY-W040194). This product is intended for research and analytical applications. Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity.
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Cat. No.: HY-P86053
Synonyms: ATN; CMM8; LB24 AB; LB24-AB; Monophenol monooxygenase; OCA1; OCA1A; OCAIA; Oculocutaneous albinism IA; SHEP3; SK29 AB; SK29-AB; Tumor rejection antigen AB; TYR; TYRO_HUMAN; tyrosinase; oculocutaneous albinism IA; Tyrosinase

Host:  

Mouse

Application:  

IHC-P, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85966
Synonyms: ATN; CMM8; LB24 AB; LB24-AB; Monophenol monooxygenase; OCA1; OCA1A; OCAIA; Oculocutaneous albinism IA; SHEP3; SK29 AB; SK29-AB; Tumor rejection antigen AB; TYR; TYRO_HUMAN; tyrosinase; oculocutaneous albinism IA; Tyrosinase

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-189229
Target:  

HPPD Drug Derivative

Research Areas:  

Others

HPPD-IN-16 is a potent HPPD inhibitor with an IC50 of 0.146 μM against AtHPPD. HPPD-IN-16 blocks HPPD enzymatic activity, interferes with the biosynthesis of plastoquinone and tocopherol, and causes plant death due to albinism resulting from the lack of photosynthetic pigments. HPPD-IN-16 can be used in herbicide research .
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Cat. No.: HY-189010
Target:  

Herbicide HPPD

Research Areas:  

Others

HPPD-IN-13 is a potent herbicide targeting HPPD, with an IC50 value of 0.132 μM against EcHPPD. HPPD-IN-13 primarily forms bidentate coordination with the ferrous ion in the active site of HPPD, and competitively blocks HPPA metabolism via π-π stacking and multiple hydrogen bonds, ultimately leading to plant albinism and death. HPPD-IN-13 can be used in the research and development of novel bleaching herbicides .
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Cat. No.: HY-P706177
Purity:  ≥ 90%, as determined by SDS-PAGE.
Synonyms: OCA2; Oculocutaneous albinism II (Pink-Eye Dilution Homolog, Mouse); Prev. D15S12; Eye Color 2 (Central Brown); Prev. P; Eye Color 3 (Brown); Prev. EYCL2; P-Protein; Prev. EYCL3; P Protein; Melanocyte-Specific Transporter Protein; Total Brown Iris Pigment
Species:  
Virus
Source:  
E. coli
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