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aliphatic glucosinolate

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By Targets:	Apoptosis (1) Bacterial (1) Drug Derivative (1) Endogenous Metabolite (2) Lipase (1) NF-κB (1) p38 MAPK (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N10346A

Gluconapin 3-Butenyl glucosinolate	Lipase Bacterial	Infection Cancer
Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity .

HY-N10347

11-(Methylsulfinyl)undecyl-glucosinolate	Others	Others
11-(Methylsulfinyl)undecyl-glucosinolate is an aliphatic glucosinolate .

HY-N10345

Glucobrassicanapin potassium 4-Pentenylglucosinolate potassium	Others	Others
Glucobrassicanapin (4-Pentenylglucosinolate) potassium is an aliphatic glucosinolate in vegetable crops of Brassica rapa .

HY-W714675

Glucoiberin	Endogenous Metabolite	Cancer
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

HY-N10346

Gluconapin potassium 3-Butenyl glucosinolate potassium	Endogenous Metabolite	Infection Cancer
Gluconapin (3-Butenyl glucosinolate) potassium is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin potassium inhibits the elevation of plasma triglyceride levels in mice. Gluconapin potassium also exhibits certain antibacterial activity .

HY-W702980

Desulfoglucoraphanin	Drug Derivative	Others
Desulfoglucoraphanin is an aliphatic glucosinolate present in Brassica rapa L. ssp. pekinensis. Desulfoglucoraphanin is the desulfated derivative of Glucoraphanin (HY-N4068) .

HY-N2423B

(E/Z)-Sinigrin free base (E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base	NF-κB p38 MAPK Apoptosis	Cardiovascular Disease Infection Inflammation/Immunology Cancer
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC₅₀ of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .

Gluconapin 3-Butenyl glucosinolate	Structural Classification Brassica rapa L. Ketones, Aldehydes, Acids Plants Brassicaceae Source Classification	Lipase Bacterial
Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity .

11-(Methylsulfinyl)undecyl-glucosinolate	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification	Others
11-(Methylsulfinyl)undecyl-glucosinolate is an aliphatic glucosinolate .

Glucoiberin	Structural Classification Iberis amara L. Plants Brassicaceae Saccharides Monosaccharides Source Classification	Endogenous Metabolite
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

Gluconapin potassium 3-Butenyl glucosinolate potassium	Structural Classification Brassica rapa L. Classification of Application Fields Ketones, Aldehydes, Acids Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Gluconapin (3-Butenyl glucosinolate) potassium is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin potassium inhibits the elevation of plasma triglyceride levels in mice. Gluconapin potassium also exhibits certain antibacterial activity .

Desulfoglucoraphanin	Structural Classification Natural Products Plants Brassicaceae Source Classification	Drug Derivative
Desulfoglucoraphanin is an aliphatic glucosinolate present in Brassica rapa L. ssp. pekinensis. Desulfoglucoraphanin is the desulfated derivative of Glucoraphanin (HY-N4068) .

(E/Z)-Sinigrin free base (E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base	Structural Classification Glucosinolates Plants Brassicaceae Source Classification Mutarda nigra (L.) Bernh.	NF-κB p38 MAPK Apoptosis
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC₅₀ of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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aliphatic glucosinolate

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