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  3. Lipase Bacterial
  4. Gluconapin

Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity.

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Gluconapin

Gluconapin Chemical Structure

CAS No. : 19041-09-9

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Gluconapin Related Antibodies

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Description

Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity[1][2][3].

In Vitro

Gluconapin (4 mM) exhibits weak inhibitory activity against porcine pancreatic lipase, inhibiting only 5.7% of the enzyme activity[2].
Gluconapin (0.15-3.0 μL/mL; 18 h) dose-dependently inhibits the growth of Xanthomonas campestris pv. campestris race 4 strain HRI1279A in vitro[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gluconapin Related Antibodies
In Vivo

Gluconapin (40-80 μmol/kg; oral administration; single dose immediately before corn oil loading) can inhibit corn oil-induced postprandial increase in plasma triglycerides in male Slc:ddY mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Slc:ddY mice (6-week-old, male)[2]
Dosage: 40 μmol/kg (14.9 mg/kg); 80 μmol/kg (29.8 mg/kg)
Administration: p.o.; single dose (immediately before corn oil loading)
Result: Showed a non-statistically significant tendency to decrease plasma triglyceride levels at 4-8 hours after administration (40 μmol/kg).
Significantly suppressed the elevation of plasma triglyceride levels at 3-8 hours after administration, and reduced the 8-hour area under the plasma triglyceride concentration curve (AUC) to 61.5 ± 6.8% of the control value (p < 0.05 vs.control) (80 μmol/kg).
Molecular Weight

373.40

Formula

C11H19NO9S2
CAS No.
SMILES

O=S(O/N=C(CCC=C)\S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)(O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Gluconapin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gluconapin19041-09-93-Butenyl glucosinolateLipaseBacterialnitrilespostprandial hypertriglyceridemiaaliphatic glucosinolateepithionitrilesblack rotmiceInhibitorinhibitorinhibit

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