Gluconapin
Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity.
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- CAS. Nr.: 19041-09-9
- Formel: C11H19NO9S2
- Molecular Weight:373.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Gluconapin (4 mM) exhibits weak inhibitory activity against porcine pancreatic lipase, inhibiting only 5.7% of the enzyme activity[2].
Gluconapin (0.15-3.0 μL/mL; 18 h) dose-dependently inhibits the growth of Xanthomonas campestris pv. campestris race 4 strain HRI1279A in vitro[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Slc:ddY mice (6-week-old, male)[2]
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Dosage:40 μmol/kg (14.9 mg/kg); 80 μmol/kg (29.8 mg/kg)
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Administration:p.o.; single dose (immediately before corn oil loading)
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Result:Showed a non-statistically significant tendency to decrease plasma triglyceride levels at 4-8 hours after administration (40 μmol/kg).
Significantly suppressed the elevation of plasma triglyceride levels at 3-8 hours after administration, and reduced the 8-hour area under the plasma triglyceride concentration curve (AUC) to 61.5 ± 6.8% of the control value (p < 0.05 vs.control) (80 μmol/kg).
Chemical Information
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CAS. Nr. 19041-09-9
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Molecular Weight 373.40
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Formel C11H19NO9S2
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SMILES
O=S(O/N=C(CCC=C)\S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)(O)=O
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Synonyms
3-Butenyl glucosinolate
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Padilla G, et al. Variation of glucosinolates in vegetable crops of Brassica rapa. Phytochemistry. 2007;68(4):536-545. [Content Brief]
[3]. Velasco P, et al. In vivo and in vitro effects of secondary metabolites against Xanthomonas campestris pv. campestris. Molecules. 2013;18(9):11131-11143. Published 2013 Sep 11. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Gluconapin Related Classifications
HY-N10346A Related Classifications
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