rhodium(I) tetrafluoroborate](https://file.medchemexpress.com/product_pic/hy-w010685.gif "Click to View [1,4-BIs(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
amination
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "amination" in MCE Product Catalog:
Cat. No.: HY-Y0006
CAS No.: 564483-18-7
Synonyms: 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
Cat. No.: HY-W590989
CAS No.: 2489525-81-5
Synonyms: GPhos Pd G6 TES
Target:
Research Areas:
GPhos Pd G6 (GPhos Pd G6 TES) is a palladium catalyst. GPhos Pd G6 catalyzes the Buchwald-Hartwig amination reaction and promotes C-N bond formation between aryl chlorides and amines. GPhos Pd G6 is a pharmaceutical intermediate used for the synthesis of various active compounds .
Cat. No.: HY-W008137
CAS No.: 62802-38-4
Cat. No.: HY-D1336
CAS No.: 2183440-42-6
Cat. No.: HY-W000438
CAS No.: 105838-14-0
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N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .
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Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues .
Cat. No.: HY-W003601
CAS No.: 357927-50-5
Cat. No.: HY-W040209
CAS No.: 846-63-9
Synonyms: α-NPO
Research Areas:
IC 86621 is a potent DNA-dependent protein kinase (DNA-PK) inhibitor, with an IC50 of 120 nM. IC 86621 also acts as a selective and reversible ATP-competitive inhibitor.IC 86621 inhibits DNA-PK mediated cellular DNA double-strand break (DSB) repair (EC50=68 µM). IC 86621 increases DSB-induced antitumor activity without cytotoxic effects. IC 86621 can protects rheumatoid arthritis (RA) T cells from apoptosis .
Cat. No.: HY-W004606
CAS No.: 6267-02-3
Synonyms: DM-AD
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9,9-Dimethyl-9,10-dihydroacridine (DM-AD) is an electron-donating group with hole transport mobility, which serves as a building block for the synthesis of organic semiconductors and light-emitting emitters. 9,9-Dimethyl-9,10-dihydroacridine can form donor-acceptor-donor type thermally activated delayed fluorescence emitters. 9,9-Dimethyl-9,10-dihydroacridine undergoes oxidation to form radical cations, which further participate in dimerization or oligomerization reactions .
Cat. No.: HY-117293
CAS No.: 19792-91-7
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Phenyl sulfamate is a nitrogen source that can be used in the amination of intermolecular .
Cat. No.: HY-W021597
CAS No.: 182344-70-3
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N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination .
Cat. No.: HY-W145053
CAS No.: 149358-73-6
Synonyms: Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate
ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
Cat. No.: HY-W099634
CAS No.: 540-08-9
Synonyms: Heptadecan-9-one
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9-Heptadecanone (Heptadecan-9-one) is an aliphatic molecule with a central ketone on a C17 chain. The ketone may react with amines in reductive aminations to link this molecule to larger lipid structures.
Cat. No.: HY-W451211
CAS No.: 1447701-63-4
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Thalidomide-5-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
Cat. No.: HY-W586329
CAS No.: 2369068-46-0
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Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
Cat. No.: HY-W010685
CAS No.: 79255-71-3
Synonyms: [Rh(dppb)(COD)]BF4
Research Areas:
[1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate ([Rh(dppb)(COD)]BF4) serves as a rhodium-based catalyst that facilitates regioselective hydrogenation and enantioselective reductive amination reactions.
Cat. No.: HY-W800837
CAS No.: 2231240-82-5
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t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
Cat. No.: HY-W800619
CAS No.: 2055024-61-6
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NH2-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
