27 Results for "

amination

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "amination" in MCE Product Catalog:

Cat. No.: HY-Y0006
CAS No.: 564483-18-7
Synonyms: 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters .
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Cat. No.: HY-W590989
CAS No.: 2489525-81-5
Synonyms: GPhos Pd G6 TES
Target:  

Drug Intermediate

Research Areas:  

Others

GPhos Pd G6 (GPhos Pd G6 TES) is a palladium catalyst. GPhos Pd G6 catalyzes the Buchwald-Hartwig amination reaction and promotes C-N bond formation between aryl chlorides and amines. GPhos Pd G6 is a pharmaceutical intermediate used for the synthesis of various active compounds .
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Cat. No.: HY-W008137
CAS No.: 62802-38-4
5-Bromo-2-fluoropyrimidine is a polyhalogenated pyrimidine and chemoselective amination substrate.5-Bromo-2-fluoropyrimidine undergoes chemoselective amination at the C-2 position (C-F bond) with no amination at the C-5 position (C-Br bond) in the presence of a Cu(II)/PTABS catalytic system .
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Cat. No.: HY-D1336
CAS No.: 2183440-42-6
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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Cat. No.: HY-W000438
CAS No.: 105838-14-0
Research Areas:  

Others

N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .
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Cat. No.: HY-114351
CAS No.: 178388-71-1
Purity:  97.40%
Target:  

Fluorescent Dye

Research Areas:  

Others

BODIPY FL hydrazide is a BODIPY-containing hydrazide fluorescent dye. BODIPY FL hydrazide is used to label carbonyl groups on oxidatively damaged proteins, 3-ketosteroids, and heparin/heparan sulfate carbohydrates. BODIPY FL hydrazide specifically binds to protein carbonyls, steroid keto groups, or reducing-end carbonyls of carbohydrates through derivatization or reductive amination via its hydrazide group to form stable conjugates; after the reaction is complete, the labeled molecules emit strong fluorescence (Ex/Em = 488-495/516-520 nm) .
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Cat. No.: HY-W007317
CAS No.: 578-66-5
8-Aminoquinoline is a chelating ligand and intermediate. 8-Aminoquinoline assists metal-catalyzed direct C (sp 2)-H and unactivated C (sp 3)-H bond functionalization, copper-mediated C-H/C-H coupling, as well as copper/silver-catalyzed aryl C (sp 2)-H amination reactions. 8-Aminoquinoline forms cationic Pt (II) complexes with anti-tumor activity. 8-Aminoquinoline is used in research related to latent malaria, glioblastoma, pancreatic adenocarcinoma, adenocarcinoma and biphasic mesothelioma .
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Cat. No.: HY-D0099
CAS No.: 76863-28-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Fluorescein-5-thiosemicarbazide is a green fluorescent probe used for carbonyl labeling. The thiosemicarbazide group of FTSC reacts with aldehyde groups at the reducing ends of carbohydrates via reductive amination, and can also undergo chemoselective ligation with ketone groups in systems such as 2-keto Ac4GalNAc to form stable fluorescent derivatives. FTSC is applicable for fluorescent labeling of carbohydrates and enables fluorescence imaging of mucin-type O-linked glycoproteins in the 2-keto Ac4GalNAc metabolic labeling system. Free FTSC exhibits Ex/Em = 495/517 nm in PBS. FTSC is suitable for carbohydrate labeling and cellular glycosylation imaging studies .
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Cat. No.: HY-P2768
CAS No.: 9082-71-7
Synonyms: LDH, EC 1.4.1.9
Research Areas:  

Metabolic Disease

Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues .
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Cat. No.: HY-W003601
CAS No.: 357927-50-5
2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.
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Cat. No.: HY-W002925
CAS No.: 213697-53-1
Target:  

Drug Intermediate

Research Areas:  

Others

DavePhos is a phosphine ligand and electron donor. DavePhos can form cationic rhodium complexes to promote the selective hydrocarboxylation of styrene derivatives with CO2 and H2. As a sacrificial electron donor, DavePhos assists in generating active Rh-H species to initiate the catalytic cycle. DavePhos can be used in Buchwald−Hartwig cross-coupling reactions within palladium-based catalytic systems. DavePhos is applicable to platinum-catalyzed reductive amination of amine-acid .
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Cat. No.: HY-W040209
CAS No.: 846-63-9
Synonyms: α-NPO
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .
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Cat. No.: HY-117293
CAS No.: 19792-91-7
Target:  

Drug Intermediate

Research Areas:  

Others

Phenyl sulfamate is a nitrogen source that can be used in the amination of intermolecular .
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Cat. No.: HY-W021597
CAS No.: 182344-70-3
Target:  

Drug Intermediate

Research Areas:  

Others

N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination .
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Cat. No.: HY-W145053
CAS No.: 149358-73-6
Synonyms: Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate
Target:  

Factor Xa Bacterial

Research Areas:  

Infection

ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
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Cat. No.: HY-W099634
CAS No.: 540-08-9
Synonyms: Heptadecan-9-one
Research Areas:  

Others

9-Heptadecanone (Heptadecan-9-one) is an aliphatic molecule with a central ketone on a C17 chain. The ketone may react with amines in reductive aminations to link this molecule to larger lipid structures.
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Cat. No.: HY-W451211
CAS No.: 1447701-63-4
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

Thalidomide-5-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
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Cat. No.: HY-W586329
CAS No.: 2369068-46-0
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
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Cat. No.: HY-W010685
CAS No.: 79255-71-3
Synonyms: [Rh(dppb)(COD)]BF4
Research Areas:  

Others

[1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate ([Rh(dppb)(COD)]BF4) serves as a rhodium-based catalyst that facilitates regioselective hydrogenation and enantioselective reductive amination reactions.
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Cat. No.: HY-W800837
CAS No.: 2231240-82-5
Target:  

ADC Linkers

Research Areas:  

Cancer

t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
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