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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
antiandrogen activity
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "antiandrogen activity" in MCE Product Catalog:
26
Target:
Research Areas:
Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.
25
Target:
Research Areas:
Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).
Cat. No.: HY-W011848
CAS No.: 2528-16-7
Synonyms: 2-((Benzyloxy)carbonyl)benzoic acid
Target:
Cat. No.: HY-70013S
CAS No.: 2122245-62-7
Synonyms: CB-7598-d4
Cat. No.: HY-75054R
CAS No.: 154229-18-2
Synonyms: CB7630 (Standard)
Target:
Research Areas:
Abiraterone acetate (Standard) is the analytical standard of Abiraterone acetate. This product is intended for research and analytical applications. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).
Cat. No.: HY-159844
CAS No.: 2446929-86-6
Target:
Research Areas:
Gridegalutamide has antiandrogen and antitumor activities .
Target:
Research Areas:
Abiraterone sulfate is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity .
Cat. No.: HY-137193
CAS No.: 219843-75-1
Target:
Research Areas:
5,6-Dihydroabiraterone is the metabolism of Abiraterone (HY-70013). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, and shows antitumor activity in CRPC (castration-resistant prostate cancer) .
Cat. No.: HY-137444
CAS No.: 124548-08-9
Target:
Research Areas:
Ludaterone is an antiandrogen agent, with potent antiandrogenic activity .
Target:
Research Areas:
SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity .
Cat. No.: HY-N9917
CAS No.: 929042-36-4
Synonyms: 6′-O-Galloylalbiflorin
Target:
Cat. No.: HY-W653896
CAS No.: 2469262-26-6
Cat. No.: HY-178938
CAS No.: 1182011-65-9
Research Areas:
AR Degrader-3 is an orally active molecular glue that targets AR/ARV7 and induces the degradation of AR and ARV7 through the ubiquitin-proteasome pathway (UPP). AR Degrader-3 directly interacts with the ligand-binding domain (LBD) and the N-terminal domain (NTD) of AR. AR Degrader-3 effectively suppresses the transcriptional activity of wild-type AR (AR-WT), AR mutants, and ARV7. AR Degrader-3 downregulates the mRNA and protein levels of downstream AR target genes, thereby overcoming antiandrogen resistance mediated by ARV7 and AR point mutations. AR Degrader-3 induces apoptosis in Enzalutamide (HY-70002) (ENZa)-resistant cells and increases cleaved caspase-3 protein levels. AR Degrader-3 can be used for the study of castration-resistant prostate cancer (CRPC) .
Cat. No.: HY-148376
CAS No.: 2378463-76-2
Target:
Research Areas:
Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity .
Cat. No.: HY-106104
CAS No.: 83646-86-0
Synonyms: RU-38882; RU-882
Target:
Research Areas:
Inocoterone acetate (RU-38882) is a nonsteroidal antiandrogen. Inocoterone acetate binds to the androgen receptor and has antiandrogenic activity in animal models. Inocoterone acetate reduces inflammatory papules and pustules .
Cat. No.: HY-137389
CAS No.: 154229-20-6
Target:
Research Areas:
Anhydro abiraterone is a degradation product of Abiraterone acetate (HY-75054). Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity .
Cat. No.: HY-152512
Target:
Research Areas:
RLA-4842 is an iron activator containing anti-androgen. RLA-4842 has anti-proliferative activity on metastatic castration-resistant prostate cancer (mCRPC) cell line .
Cat. No.: HY-152520
Target:
Research Areas:
RLA-5331 is an iron activator containing anti-androgen. RLA-5331 has anti-proliferative activity on metastatic castration-resistant prostate cancer (mCRPC) cell line .
Cat. No.: HY-75054S
CAS No.: 2122245-63-8
Synonyms: CB7630-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
