45 Results for "

antiarthritic

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "antiarthritic" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-16291
CAS No.: 916151-99-0
Synonyms: LOR-253; LT-253
Target:  

c-Myc KLF Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor . APTO-253 has antiarthritic activity .
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10
10 Cited Publications
Cat. No.: HY-N2897
CAS No.: 480-20-6
Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents .
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9
9 Cited Publications
Cat. No.: HY-N0705
CAS No.: 85643-19-2
Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway .
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3
3 Cited Publications
Cat. No.: HY-N2513
CAS No.: 631-69-6
β-Boswellic acid is isolated from the gum resin of Boswellia serrata with anticancer, antioxidant activity, anti-inflammatory activity and anti-arthritic pain.β-Boswellic acid is an orally active nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells with IC50 values ranging from 0.6 to 7.1 μM. β-Boswellic acid is promising for research of diabetes, inflammatory and arthritic diseases .
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3
3 Cited Publications
Cat. No.: HY-N0354
CAS No.: 84-65-1
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis .
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3
3 Cited Publications
Cat. No.: HY-12511
CAS No.: 72873-74-6
Purity:  99.91%
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology

SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid .
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2
2 Cited Publications
Cat. No.: HY-B1456A
CAS No.: 29679-58-1
Synonyms: LILLY-53858
Research Areas:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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2
2 Cited Publications
Cat. No.: HY-N6647
CAS No.: 20633-84-5
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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2
2 Cited Publications
Cat. No.: HY-B0288B
CAS No.: 71720-56-4
Synonyms: LILLY-53858 Calcium hydrate
Research Areas:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) Calcium hydrate is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium hydrate is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium hydrate also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium hydrate has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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1
1 Cited Publications
Cat. No.: HY-108065A
CAS No.: 128596-80-5
Purity:  ≥98.0%
Synonyms: 3'-SL sodium
3'-Sialyllactose (3'-SL) sodium is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose sodium is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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1
1 Cited Publications
Cat. No.: HY-N4136
CAS No.: 25694-72-8
Synonyms: Veronicastroside
Lonicerin (Veronicastroside) is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE). Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties .
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Cat. No.: HY-129566
CAS No.: 56973-41-2
Purity:  98.52%
Withanolide B is an active component of W. somnifera Dunal. Withanolide B promotes osteogenic differentiation of hBMSCs via ERK1/2 and Wnt/β-catenin signaling pathways. Withanolide B exhibits neuroprotective, anti-arthritic, anti-aging and anti-cancer effects .
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Cat. No.: HY-108065
CAS No.: 35890-38-1
Synonyms: 3'-SL
3'-Sialyllactose (3'-SL) is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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Cat. No.: HY-106087
CAS No.: 98320-39-9
Purity:  98.96%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
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Cat. No.: HY-B0288A
CAS No.: 34597-40-5
Synonyms: LILLY-53858 Calcium
Research Areas:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) Calcium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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Cat. No.: HY-105808
CAS No.: 38873-55-1
Purity:  99.87%
Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue .
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Cat. No.: HY-107360
CAS No.: 64808-48-6
Purity:  99.94%
Synonyms: CCA
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent .
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Cat. No.: HY-N2843
CAS No.: 22255-10-3
α-Amyrin palmitate is isolated from Santalum album (sandalwood). α-Amyrin palmitate can be used for the study of arthritis in vivo .
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Cat. No.: HY-120529
CAS No.: 134044-97-6
Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.
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Cat. No.: HY-105808R
CAS No.: 38873-55-1
Furobufen (Standard) is the analytical standard of Furobufen. This product is intended for research and analytical applications. Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue .
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