Lobenzarit disodium
Based on 1 Customer Validation
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 64808-48-6
- Formula: C14H8ClNNa2O4
- Molecular Weight:335.65
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Lobenzarit disodium (CCA) inhibits chemiluminescence induced by activated oxygen with an IC50 of 1.6 μM[1].
Lobenzarit disodium (0.3-300 μM) inhibits the production of lipid peroxide and the IgG alteration induced by UV irradiation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Sprague-Dawley rats[2]
-
Dosage:10 and 50 mg/kg
-
Administration:IP; daily for 7 days
-
Result:Showed anti-arthritic effect, but had no therapeutic effect in arthritic rats which were depleted of T lymphocytes.
Chemical Information
-
CAS No. 64808-48-6
-
Appearance Solid
-
Molecular Weight 335.65
-
Formula C14H8ClNNa2O4
-
Color White to off-white
-
SMILES
O=C(O[Na])C(C=CC(Cl)=C1)=C1NC2=C(C=CC=C2)C(O[Na])=O
-
Synonyms
CCA
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 4.85 mg/mL (14.45 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9793 mL | 14.8963 mL | 29.7926 mL | 74.4815 mL |
| 5 mM | 0.5959 mL | 2.9793 mL | 5.9585 mL | 14.8963 mL | |
| 10 mM | 0.2979 mL | 1.4896 mL | 2.9793 mL | 7.4481 mL |