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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
106 Results for "
antimetastatic
" in MedChemExpress (MCE) Product Catalog:
Products (106)
106 Results for "antimetastatic" in MCE Product Catalog:
24
24 Publications Verification
Art. -Nr.: HY-B0617
CAS. Nr.: 29908-03-0
Synonyms: S-Adenosyl methionine; Ademetionine; AdoMet
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
23
23 Cited Publications
Art. -Nr.: HY-W017770
CAS. Nr.: 97540-22-2
Synonyms: Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate
Target:
22
22 Cited Publications
Art. -Nr.: HY-B0617A
CAS. Nr.: 52248-03-0
Synonyms: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate
Category:
Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
19
19 Cited Publications
Synonyms: S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide
Target:
13
Target:
Forschungsgebiete:
Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect .
13
Category:
Animals Macrolide Antibiotics Antibiotics Marine natural products Other Diseases Sponge Disease Research Anticancer Disease Research Fields
Target:
13
13 Cited Publications
Art. -Nr.: HY-19928A
CAS. Nr.: 1352610-25-3
Synonyms: EW-7197 Hydrochloride; TEW-7197 Hydrochloride
Target:
Forschungsgebiete:
Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect .
11
11 Cited Publications
Synonyms: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride
Target:
Forschungsgebiete:
S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is an orally active methyl group donor. S-Adenosyl-L-methionine chloride dihydrochloride is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine chloride dihydrochloride also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine chloride dihydrochloride has the potential for, cancer, liver disease and osteoarthritis research .
9
9 Cited Publications
1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo .
8
Category:
Cardiovascular Disease Polygonaceae Reynoutria japonica Houtt. Coumarins Plants Microorganisms Monophenols Phenols Phenylpropanoids Disease Research Fields
Target:
6
6 Cited Publications
Art. -Nr.: HY-N2022
CAS. Nr.: 79831-76-8
Target:
5
5 Cited Publications
Art. -Nr.: HY-N1376
CAS. Nr.: 38243-03-7
Synonyms: (20R)-Propanaxadiol; R-ginsenoside Rg3
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer
Target:
5
Category:
Oleaceae Fraxinus rhynchophylla Hance Coumarins Plants other families Monophenols Phenols Phenylpropanoids Disease Research Fields Inflammation/Immunology
Target:
3
3 Cited Publications
Art. -Nr.: HY-N2322
CAS. Nr.: 32449-98-2
Category:
Alkaloids Piperidine Alkaloids Solanum nigrum Linn. Plants Solanaceae Disease Research Fields Cancer
Target:
2
DMAPT (Dimethylamino Parthenolide), an analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect .
2
2 Cited Publications
Forschungsgebiete:
OB-24 is a selective small-molecule HO-1 inhibitor (IC50 = 1.9 μM for HO-1 and IC50 for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis .
1
Target:
Forschungsgebiete:
Trabedersen (AP 12009) is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma .
1
1 Cited Publications
Target:
Forschungsgebiete:
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ∼10 nM. MSX-122 has anti-inflammatory and anti-metastatic activity.
1
1 Cited Publications
Art. -Nr.: HY-N6036
CAS. Nr.: 98665-15-7
Category:
Triterpenes Microorganisms Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields Cancer
Target:
1
1 Cited Publications
Target:
Forschungsgebiete:
BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
