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BDP-13176 

Cat. No.: HY-111578 Purity: 98.64%
Handling Instructions

BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent.

For research use only. We do not sell to patients.

BDP-13176 Chemical Structure

BDP-13176 Chemical Structure

CAS No. : 2290660-61-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 383 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1].

In Vitro

BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

497.38

Formula

C₂₄H₂₂Cl₂N₆O₂

CAS No.

2290660-61-4

SMILES

O=C(NC1=CC=NC=C1)C(C2=C3C=NN2C4CCNCC4)=CN(CC5=CC=C(Cl)C(Cl)=C5)C3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (502.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0105 mL 10.0527 mL 20.1054 mL
5 mM 0.4021 mL 2.0105 mL 4.0211 mL
10 mM 0.2011 mL 1.0053 mL 2.0105 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.18 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.18 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.18 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

BDP-13176BDP13176BDP 13176OthersInhibitorinhibitorinhibit

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Product Name:
BDP-13176
Cat. No.:
HY-111578
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