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beta-lactam antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (111) Apoptosis (5) Aurora Kinase (8) Bacterial (120) Beta-lactamase (26) Biochemical Assay Reagents (6) Cytochrome P450 (1) DNA/RNA Synthesis (3) Drug Intermediate (5) Drug Metabolite (3) Endogenous Metabolite (1) Environmental Pollutants (1) Estrogen Receptor/ERR (1) Fungal (1) GSK-3 (6) Histamine Receptor (3) HSP (3) Interleukin Related (1) Isotope-Labeled Compounds (9) Orthopoxvirus (3) p38 MAPK (1) Parasite (3) Penicillin-binding protein (PBP) (15) PKC (1) Reference Standards (34) TNF Receptor (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (3) Endocrinology (2) Infection (135) Inflammation/Immunology (15) Metabolic Disease (2) Neurological Disease (1)
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148

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Click Chemistry

Targets Recommended: Antibiotic

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-B0522

Ampicillin Maximum Cited Publications 80 Publications Verification D-(-)-α-Aminobenzylpenicillin	Bacterial Antibiotic	Infection
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-B0522A

Ampicillin sodium Maximum Cited Publications 80 Publications Verification D-(-)-α-Aminobenzylpenicillin sodium salt	Bacterial Antibiotic	Infection
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B0425

Novobiocin 10+ Cited Publications Albamycin; Cathomycin	Antibiotic DNA/RNA Synthesis HSP Apoptosis Bacterial Orthopoxvirus	Infection Cancer
Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity .

HY-B1463

Penicillin G sodium salt 20+ Cited Publications Benzylpenicillin sodium salt	Beta-lactamase Bacterial Antibiotic	Infection
Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-B0974

Methicillin sodium salt 5+ Cited Publications Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-B0425A

Novobiocin sodium 10+ Cited Publications Albamycin sodium; Cathomycin sodium	Bacterial Antibiotic Orthopoxvirus Apoptosis DNA/RNA Synthesis HSP	Infection Cancer
Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity .

HY-B0129

Aztreonam 15+ Cited Publications SQ-26,776	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B1923

Piperacillin 10+ Cited Publications Pipracil	Antibiotic Bacterial Beta-lactamase Penicillin-binding protein (PBP)	Infection Cancer
Piperacillin is a semisynthetic broad-spectrum **β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins**. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-B0522B

Ampicillin trihydrate Maximum Cited Publications 80 Publications Verification D-(-)-α-Aminobenzylpenicillin trihydrate	Bacterial Antibiotic	Infection
Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-A0269

Mecillinam 4 Publications Verification Amdinocillin; FL 1060	Bacterial Antibiotic	Infection
Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-B1286

Piperacillin sodium 10+ Cited Publications Sodium piperacillin	Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection Cancer
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-148493

MK-3402	Bacterial	Infection
MK-3402 (Compound303) is a metallo-beta-lactamase inhibitor, with IC₅₀ values of 0.53, 0.25 and 0.169 nM against IMP-1, NDM-1, and VIM-1, respectively. MK-3402 can be used in bacterial research and shows a synergistic effect when used in combination with beta-lactam antibiotics .

HY-B0977

Dicloxacillin Sodium hydrate 3 Publications Verification Dicloxacillin sodium salt monohydrate	Bacterial Antibiotic	Infection Inflammation/Immunology
Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-13588

Cefsulodin sodium SCE-129 sodium	Bacterial Antibiotic	Infection
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC₅₀ value of 16 μM .

HY-B0522R

Ampicillin (Standard) D-(-)-α-Aminobenzylpenicillin (Standard)	Reference Standards Bacterial Antibiotic	Infection
Ampicillin (Standard) is the analytical standard of Ampicillin. This product is intended for research and analytical applications. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-B1275

Cephalothin sodium 3 Publications Verification Cefalotin sodium	Beta-lactamase Bacterial Antibiotic	Infection
Cephalothin (Cephalotin) sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam *antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an K_i* of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .

HY-B1275A

Cephalothin 3 Publications Verification Cephalotin	Beta-lactamase Bacterial Antibiotic	Infection Cardiovascular Disease
Cephalothin (Cephalotin) is a semi-synthetic cephalosporin antibiotic and beta-lactam *antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an K_i* of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .

HY-B0529A

Azlocillin sodium salt 1 Publications Verification Sodium azlocillin	Bacterial Parasite Antibiotic	Infection
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam *antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite* Plasmodium falciparum .

HY-B1484

Moxalactam sodium salt 1 Publications Verification Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium	Beta-lactamase Bacterial Antibiotic	Infection
Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam *antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases* .

HY-B0186B

Cefoselis sulfate FK-037	Bacterial Antibiotic	Infection
Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam *antibiotic*. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier .

HY-10004

Faropenem daloxate Faropenem medoxil	Antibiotic Bacterial	Infection
Faropenem daloxate (Faropenem medoxil) is an orally active **beta-lactam antibiotic**. Faropenem daloxate has excellent in vitro activity against Streptococcus pneumonia, Haemophilus influenza, and other key pathogens implicated in acute bacterial rhino sinusitis. Faropenem daloxate can be studied in research for respiratory pathogens and acute bacterial sinusitis .

HY-B0522S

Ampicillin-d5	Bacterial Antibiotic	Infection
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B1466

Mezlocillin sodium BAY-f 1353 sodium	Bacterial Antibiotic	Infection
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .

HY-B1252

Cefalonium	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B1459

Dicloxacillin sodium 3 Publications Verification	Beta-lactamase Bacterial Antibiotic	Infection
Dicloxacillin sodium is a **β-lactam antibiotic** of the penicillin family. Dicloxacillin sodium against Gram-positive bacteria. Dicloxacillin sodium is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-B0129S

Aztreonam-d6 SQ-26,776-d₆	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B1682A

Loracarbef hydrate	Antibiotic Bacterial	Infection
Loracarbef hydrate, a cephalosporin *antibiotic, is an orally active second-generation synthetic beta-lactam* antibiotic of the carbacephem class .

HY-19882

BAL-30072	Bacterial	Infection
BAL-30072, a siderophore sulfactam, is a monocyclic *beta-lactam* antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC₉₀ values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-W005223

(R)-Tetrahydrofuran-2-carboxylic acid (R)-(+)-Tetrahydrofuran-2-carboxylic acid	Biochemical Assay Reagents Drug Intermediate	Infection
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-121544

Methicillin	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-N7120

Penicillin G procaine hydrate PGP hydrate	Bacterial Antibiotic	Infection
Penicillin G Procaine hydrate (PGP hydrate) is a β-lactam antibiotic and sustained-release formulation. Penicillin G procaine (hydrate) hydrolyzes in vivo to release penicillin G and Procaine (HY-B0546), thereby delaying the absorption of penicillin G .

HY-16251A

Hetacillin	Bacterial	Infection
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family.

HY-B0129R

Aztreonam (Standard) SQ-26,776 (Standard)	Penicillin-binding protein (PBP) Reference Standards Bacterial Antibiotic	Infection
Aztreonam (Standard) is the analytical standard of Aztreonam. This product is intended for research and analytical applications. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-137927

Benapenem	Antibiotic	Others
Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.

HY-34588

D-4-Hydroxyphenylglycine D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine	Antibiotic	Others
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

HY-B1682

Loracarbef	Antibiotic Bacterial	Infection
Loracarbef, a cephalosporin *antibiotic, is an orally active second-generation synthetic beta-lactam* antibiotic of the carbacephem class .

HY-139628

JPD447	Bacterial	Infection Cancer
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.

HY-W764182

Cephalosporinase,bacillus	Bacterial	Infection
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to study bacterial infections .

HY-B0925S

Oxacillin-13C6 sodium	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Oxacillin- ¹³C₆ (sodium) is the ¹³C₆ labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

HY-B1466A

Mezlocillin BAY-f 1353	Antibiotic Bacterial	Infection
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .

HY-B1459A

Dicloxacillin	Beta-lactamase Bacterial Antibiotic	Infection
Dicloxacillin is a **β-lactam antibiotic** of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-16137

Cefaloglycin Cephaloglycin	Bacterial	Infection
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic *β-lactam* cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .

HY-A0035

Faropenem	Antibiotic Bacterial	Infection
Faropenem is a potent and orally active **beta-lactam antibiotic*. Faropenem demonstrates broad-spectrum in vitro* antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections .

HY-B0522C

L-(+)-Ampicillin L-(+)-α-Aminobenzylpenicillin	Antibiotic	Infection
L-(+)-Ampicillin (L-(2S) ampicillin) is the L-isomer of Ampicillin (HY-B0522). Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B1484A

Moxalactam Latamoxef; Lamoxactam; LY-127935	Beta-lactamase Bacterial Antibiotic	Infection
Moxalactam (Latamoxef) is a synthetic oxa-β-lactam *antibiotic. Moxalactam has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam inhibits production of β-lactamases* .

HY-114780

Lactivicin	Penicillin-binding protein (PBP) Bacterial	Infection
Lactivicin is a non-beta-lactam antibiotic showing beta-lactam action through binding to penicillin-binding protein (PBP). Lactivicin is moderately active against a wide range of Gram-negative bacteria and highly active against Gram-positive bacteria .

HY-136502

(E)-Aztreonam SQ-28429	Antibiotic Bacterial	Infection
(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic. (E)-Aztreonam has the potential for the research of infections caused by gram-negative pathogens .

HY-129949

Aztreonam (lysine)	Antibiotic Bacterial	Infection Cancer
Aztreonam (lysine) is a monocyclic beta-lactam *antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria* .

HY-B0522AR

Ampicillin sodium (Standard) D-(-)-α-Aminobenzylpenicillin sodium salt (Standard)	Reference Standards Bacterial Antibiotic	Infection
Ampicillin (sodium) (Standard) is the analytical standard of Ampicillin (sodium). This product is intended for research and analytical applications. Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

Cat. No.	상품명

HY-L914

Serine/Threonine Focused Covalent Fragment Library

3,208 compounds

In the research of covalent inhibitors targeting serine and threonine, scientists have found that the nucleophilicity of these hydroxyl groups is significantly enhanced due to the influence of their surrounding environment. This results in higher activity during catalytic reactions. Aspirin, which targets the non-catalytic domain serine (Ser529 in human COX1) of cyclooxygenase, exerts its anti-inflammatory effect through covalent binding. β-lactam antibiotics, which targets the catalytic domain serine of penicillin-binding proteins, interferes with bacterial cell wall synthesis.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 3,300 fragment molecules which can target serine and threonine residues and can be used for fragment-based covalent drug discovery.

Cat. No.	상품명	Type

HY-W005223

(R)-Tetrahydrofuran-2-carboxylic acid (R)-(+)-Tetrahydrofuran-2-carboxylic acid	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-W005223R

(R)-Tetrahydrofuran-2-carboxylic acid (Standard) (R)-(+)-Tetrahydrofuran-2-carboxylic acid (Standard)	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid (Standard) is an analytical standard for (R)-Tetrahydrofuran-2-carboxylic acid (HY-W005223). This product is intended for research and analytical applications. (R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

Cat. No.	상품명	Target	Research Area

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Infection
ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-B1463

Penicillin G sodium salt 20+ Cited Publications Benzylpenicillin sodium salt	Infection Plant Cell Culture Microorganisms Classification of Application Fields Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics Source Classification	Beta-lactamase Bacterial Antibiotic
Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-B0425A

Novobiocin sodium 10+ Cited Publications Albamycin sodium; Cathomycin sodium	Microorganisms Anti-inflammation/Immunoregulatory Classification of Application Fields Antibiotics Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification Cancer	Bacterial Antibiotic Orthopoxvirus Apoptosis DNA/RNA Synthesis HSP
Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity .

HY-W013549

6-Aminopenicillanic acid 6-APA	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	Drug Metabolite Bacterial
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-117108

Nocardicin A	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Nocardicin A is a beta-lactam *antibiotic* with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .

HY-W013549R

6-Aminopenicillanic acid (Standard) 6-APA (Standard)	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Drug Metabolite Reference Standards Bacterial
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

HY-N14895

Chitinovorin A	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Chitinovorin A is a β-lactam antibiotic with a weak inhibitory activity against Gram-negative bacteria .

HY-165272

Antibiotic SF-2132	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Antibiotic
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .

HY-N14896

Chitinovorin C	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Chitinovorin C is a β-lactam antibiotic with a weak inhibitory activity against Gram-negative bacteria .

HY-N15062

2-Hydroxymethylclavam	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
2-Hydroxymethylclavam is a β-lactam antibiotic. 2-Hydroxymethylclavam has antifungal activity, especially for plant pathogenic fungi .

HY-B1463R

Penicillin G sodium salt (Standard) Benzylpenicillin sodium salt (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Beta-lactam Antibiotics Source Classification	Beta-lactamase Reference Standards Bacterial Antibiotic
Penicillin G sodium salt (Standard) is the analytical standard of Penicillin G sodium salt. This product is intended for research and analytical applications. Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-N14919

Olivanic acid	Structural Classification Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Beta-lactamase Antibiotic Bacterial
Olivanic acid is a β -lactam antibiotic. Olivanic acid has the effect of anti -Gram-positive bacteria and anti-Gram-negative bacteria. Olivanic acid inhibits β-lactamase .

HY-121120

Isosulfazecin	Structural Classification Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .

HY-N19827

Monodesmoside saponin C	Triterpenes Structural Classification Terpenoids Sapindus mukorossi Gaertn. Sapindaceae Plants Source Classification	Biochemical Assay Reagents
Monodesmoside saponin C is an absorption enhancer. Monodesmoside saponin C promotes the absorption of poorly absorbable β-lactam antibiotics in the small intestine and rectum of rats. Monodesmoside saponin C has the ability to chelate Ca ²⁺. The absorption-enhancing activity of Monodesmoside saponin C is inhibited by coexisting Ca ²⁺ ions. Monodesmoside saponin C can be used in studies on absorption enhancement of β-lactam antibiotics .

Cat. No.	상품명	Chemical Structure

HY-B0522S

Ampicillin-d5
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B0129S

Aztreonam-d6
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B0925S

Oxacillin-13C6 sodium
Oxacillin- ¹³C₆ (sodium) is the ¹³C₆ labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

HY-W654157

Dicloxacillin-13C4 sodium hydrate

Dicloxacillin- ¹³C₄ sodium hydrate is the ¹³C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-A0269S

Mecillinam-d12
Mecillinam-d₁₂ is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-W746564

L-(+)-Ampicillin-d5
L-(+)-Ampicillin-d₅ (L-(+)-α-Aminobenzylpenicillin-d₅) is the deuterium labeled L-(+)-Ampicillin (HY-B0522C). L-(+)-Ampicillin (L-(2S) ampicillin) is the L-isomer of Ampicillin (HY-B0522). Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B1252AS

Cefalonium-d4 hydrate
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B1459AS

Dicloxacillin-13C4
Dicloxacillin- ¹³C₄ is the ¹³C labeled Dicloxacillin (HY-B1459A) . Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-A0294S

Ertapenem-d4

Ertapenem-d₄ (MK-0826-d₄) is deuterium labeled Ertapenem. Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-W752893

D-4-Hydroxyphenylglycine-d5-1
D-4-Hydroxyphenylglycine-d₅-1 (D-(-)-4-Hydroxyphenylglycine-d₅-1) is the deuterium labeled D-4-Hydroxyphenylglycine (HY-34588). D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

Cat. No.	상품명		Classification

HY-B2091

Azidocillin		Azide
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam *antibiotic*. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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