Search Result

Results for "

biotinylation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylin Receptor (2) Amyloid-β (1) Apoptosis (1) Bacterial (2) BCL6 (1) Biochemical Assay Reagents (41) Bombesin Receptor (2) Casein Kinase (1) Claudin (1) DNA Stain (1) DNA/RNA Synthesis (1) Drug Derivative (1) Drug-Linker Conjugates for ADC (1) EGFR (1) Exosomes (1) Fluorescent Dye (7) Gap Junction Protein (1) GCGR (2) Liposome (1) Neurokinin Receptor (1) Neuropeptide B/W Receptor (1) NF-κB (1) PROTACs (2) Proteasome (2) Reference Standards (1) Sialyltransferase (1) Src (1) Syk (1) Thyroid Hormone Receptor (1) Transmembrane Glycoprotein (2) YTHDF (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (1) Endocrinology (1) Infection (4) Inflammation/Immunology (4) Metabolic Disease (4) Neurological Disease (8)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (8) Azide (1)
Oligonucleotides:	Fluorescent Lipids (1) Pegylated Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111496

*Sulfo-NHS-SS-Biotin* sodium** 4 Publications Verification	Biochemical Assay Reagents	Others
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive *biotinylation* reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .

HY-130809

DBCO-PEG4-Biotin 4 Publications Verification	Biochemical Assay Reagents	Cancer
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W808757

Biotin-maleimide	Biochemical Assay Reagents	Others
Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators .

HY-100215

Biotin Hydrazide 2 Publications Verification	Biochemical Assay Reagents	Others
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .

HY-W332335

Sulfosuccinimidyl-6-(biotinamido)hexanoate sodium	Biochemical Assay Reagents	Others
Sulfosuccinimidyl-6-(biotinamido)hexanoate sodium is a protein crosslinker, and is a biotinylation reagentcan for labeling cell surface proteins .

HY-W040254

Biotin-LC-LC-NHS	Fluorescent Dye	Others
Biotin-LC-LC-NHS is a biotinylation reagent that contains an NHS moiety, which can react efficiently with primary amino (-NH2). Biotin-LC-LC-NHS enables simple and efficient biotinylation of antibodies, proteins, and any other primary amine-containing biomolecules in solution. Biotin-LC-LC-NHS can be used to biotinylate small molecules such as Paclitaxel (HY-B0015) for use in binding site characterization.

HY-NP0149

Sambucus Nigra Lectin (Biotinylated) SNA (Biotinylated)	Biochemical Assay Reagents	Others
Sambucus Nigra Lectin (SNA) (Biotinylated) is a terminal sialic acid (SA) residue-binding lectin with biotinylation modification. Sambucus Nigra Lectin (Biotinylated) binds specifically to terminal sialic acid residues on captured IgG and its subclasses .

HY-173176

4-(2-Azidoethyl)phenol	Biochemical Assay Reagents	Others
4-(2-Azidoethyl)phenol (Ph_N3) is a clickable APEX2 probe. 4-(2-Azidoethyl)phenol (Ph_N3) exhibits reliable labeling ability and enabled two biotinylation routes for downstream analysis .

HY-D1635

Sulfo-NHS-LC-LC-Biotin Biotin-XX-SSE	Fluorescent Dye Exosomes	Infection
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Infection
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .

HY-137341

SK-3-91	PROTACs YTHDF	Cancer
SK-3-91 is a PROTAC-type multi-kinase degrader that can jointly induce the degradation of the largest number of unique kinases (more than 125 unique kinases). SK-3-91 induces protein degradation through the ubiquitin biotinylation (E-STUB) pathway. SK-3-91 degrades YTHDF2. SK-3-91 inhibits cell proliferation and induces morphological changes. (Pink: TAE648 ligand (HY-169396); Blue: E3 ligase ligand (HY-131717); Black: Linker (HY-140819). The E3 ligase ligand and linker can form a conjugate (HY-169397)) .

HY-116872

MAC13772 1 Publications Verification	Bacterial	Infection
MAC13772 is a BioA inhibitor with an IC₅₀ of 0.28 μM against E. coli and an IC₅₀ of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-156377

Biotin-PEG7-Maleimide	Drug-Linker Conjugates for ADC	Cancer
Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .

HY-174962A

mPEG2000-Biotin	Biochemical Assay Reagents	Others
mPEG2000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P4928

Biotinyl-Amylin (mouse, rat)	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .

HY-W440886

DSPE-PEG3400-Biotin	Liposome	Others
DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-160841

Biotin-16-dCTP	DNA Stain DNA/RNA Synthesis	Others
Biotin-16-dCTP is a biotinylated deoxycytidine triphosphate that serves as an important DNA labeling substrate. Biotin-16-dCTP can be enzymatically incorporated into the 3' end of DNA probes via terminal deoxynucleotidyl transferase, forming a 1-3 nucleotide-long tail to achieve biotinylation of the probes. Biotin-16-dCTP enhances chemiluminescent detection of low-abundance targets such as specific tRNA isoacceptors through Northern blotting. Biotin-16-dCTP can also replace conventional dCTP to be integrated into single-stranded DNA generated by asymmetric polymerase chain reaction, which is applicable for bioconjugation or pull-down assays. Repeated freeze-thaw cycles of Biotin-16-dCTP should be avoided to prevent degradation of its function for probe biotinylation .

HY-W110146

*(3aS,4S,6aR)-Biotin-PEG4-Alkyne*	Biochemical Assay Reagents	Others
(3aS,4S,6aR)-Biotin-PEG4-Alkyne is an alkyne-activated biotinylation reagent. (3aS,4S,6aR)-Biotin-PEG4-Alkyne can be reacted with azides via a copper-catalyzed click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection .

HY-137340

WH-10417-099	PROTACs Casein Kinase	Cancer
WH-10417-099 is a CRBN-based PROTAC multi-kinase degrader that induces the degradation of the maximum number of unique kinases (over 125 unique kinases, such as CSNK1E and PI3Kγ) simultaneously. WH-10417-099 induces protein degradation via the ubiquitin biotinylation (E-STUB) pathway, exhibits synergistic effects with SB-405483 (HY-W1135319). The E3 ligase ligand and linker of WH-10417-099 can form the conjugate Pomalidomide 4'-PEG5-acid (HY-131647) .

HY-101218

*N-Biotinyl-6-aminohexanoic acid* N-(+)-Biotinyl-6-aminohexanoic acid	Sialyltransferase	Others
N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation .

HY-125501

Biotin-XX hydrazide Biotin-(AC5)2-hydrazide	Biochemical Assay Reagents	Others
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .

HY-148958

SNAP-Biotin	Biochemical Assay Reagents	Others
SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) .

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-181228

DBCO-PEG10-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG10-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 10 PEGs. DBCO-PEG10-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction. DBCO-PEG10-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-130809A

DBCO-PEG1000-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG1000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-P3621

Biotinyl-Glucagon (1-29), human, bovine, porcine	GCGR	Metabolic Disease
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-113930

*3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid*	Biochemical Assay Reagents	Others
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid is a SS-biotin that can be utilized in cellular proximity biotinylation assays to label interactors .

HY-172356

Biotin-PEG3700-NH2	Biochemical Assay Reagents	Others
Biotin-PEG-NH2 (Mn 3700) can be used for biotinylation of polymerized worm micelles for targeting and drug transfer to cells .

HY-130893A

Biotin-EDA TFA	Biochemical Assay Reagents	Others
Biotin-EDA TFA is a nucleophilic biotinylation reagent used for the conjugation of various substrates and identification and quantification using biotin-conjugated fluorescent labels .

HY-130809C

DBCO-PEG3400-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG3400-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809H

DBCO-PEG40000-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG40000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809I

DBCO-PEG20000-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG20000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809D

DBCO-PEG5000-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG5000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809B

DBCO-PEG2000-Biotin	Biochemical Assay Reagents	Others
DBCO-PEG2000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-174962B

mPEG5000-Biotin	Biochemical Assay Reagents	Others
mPEG5000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

HY-174962

mPEG1000-Biotin	Biochemical Assay Reagents	Others
mPEG1000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

Cat. No.	Product Name	Type

HY-111496

*Sulfo-NHS-SS-Biotin* sodium** 4 Publications Verification	Fluorescent Dye
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive *biotinylation* reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .

HY-148958

SNAP-Biotin	Fluorescent Dye
SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .

HY-W591335

Biotin-PEG5-OH Biotin-PEG5-alcohol	Fluorescent Dye
Biotin-PEG5-OH (Biotin-PEG5-alcohol) is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.

Cat. No.	Product Name	Type

HY-W808757

Biotin-maleimide	Biochemical Assay Reagents
Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators .

HY-100215

Biotin Hydrazide 2 Publications Verification	Biochemical Assay Reagents
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-NP0149

Sambucus Nigra Lectin (Biotinylated) SNA (Biotinylated)	Biochemical Assay Reagents
Sambucus Nigra Lectin (SNA) (Biotinylated) is a terminal sialic acid (SA) residue-binding lectin with biotinylation modification. Sambucus Nigra Lectin (Biotinylated) binds specifically to terminal sialic acid residues on captured IgG and its subclasses .

HY-D0980

Biotin-DADOO

Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin

Biochemical Assay Reagents

Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-174962A

mPEG2000-Biotin	Biochemical Assay Reagents
mPEG2000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

HY-W440886

DSPE-PEG3400-Biotin	Biochemical Assay Reagents
DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.

HY-125501

Biotin-XX hydrazide Biotin-(AC5)2-hydrazide	Biochemical Assay Reagents
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .

HY-130809A

DBCO-PEG1000-Biotin	Biochemical Assay Reagents
DBCO-PEG1000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-172356

Biotin-PEG3700-NH2	Biochemical Assay Reagents
Biotin-PEG-NH2 (Mn 3700) can be used for biotinylation of polymerized worm micelles for targeting and drug transfer to cells .

HY-130893A

Biotin-EDA TFA	Biochemical Assay Reagents
Biotin-EDA TFA is a nucleophilic biotinylation reagent used for the conjugation of various substrates and identification and quantification using biotin-conjugated fluorescent labels .

HY-130809C

DBCO-PEG3400-Biotin	Biochemical Assay Reagents
DBCO-PEG3400-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809H

DBCO-PEG40000-Biotin	Biochemical Assay Reagents
DBCO-PEG40000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809I

DBCO-PEG20000-Biotin	Biochemical Assay Reagents
DBCO-PEG20000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809D

DBCO-PEG5000-Biotin	Biochemical Assay Reagents
DBCO-PEG5000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809B

DBCO-PEG2000-Biotin	Biochemical Assay Reagents
DBCO-PEG2000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-174962B

mPEG5000-Biotin	Biochemical Assay Reagents
mPEG5000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

HY-174962

mPEG1000-Biotin	Biochemical Assay Reagents
mPEG1000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .

HY-137425

*N-Biotinyl-12-aminododecanoic acid*	Biochemical Assay Reagents
N-Biotinyl-12-aminododecanoic acid is a compound formed by linking biotin and 12-aminododecanoic acid through an amide bond. N-Biotinyl-12-aminododecanoic acid is used as a biotinylation reagent to test the ligation activity of SimL .

HY-172356A

Biotin-PEG-NH2 (MW 5300)	Biochemical Assay Reagents
Biotin-PEG-NH2 (Mn 5300) can be used for biotinylation of polymerized worm micelles for targeting and drug transfer to cells .

HY-130809E

DBCO-PEG10000-Biotin	Biochemical Assay Reagents
DBCO-PEG10000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-100215R

Biotin Hydrazide (Standard)	Biochemical Assay Reagents
Biotin Hydrazide (Standard) is the analytical standard of Biotin Hydrazide (HY-100215). This product is intended for research and analytical applications. Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-W1123937C

Biotin-PEG5000-CHO	Biochemical Assay Reagents
Biotin-PEG-CHO (with a molecular weight of 5000) is a biotin-attached PEG derivative that can be used for biotinylation of biological molecules or other material surfaces. Biotin can be easily detected through the biotin/streptavidin binding test, and is widely used in molecular targeted detection.

Cat. No.	Product Name	Target	Research Area

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P10244F

Biotin-YVAD-FMK	Peptides	Infection
Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P4928

Biotinyl-Amylin (mouse, rat)	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-P4752

*KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2*	Peptides	Others
KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) .

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-P4765

*Neuropeptide Y-Lys(biotinyl) free acid (human, rat)*	Peptides	Others
Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5113A

*Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide TFA*	Peptides	Others
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide TFA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4634

*(Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5115

*(Lys(Me,Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl)*	Peptides	Others
(Lys(Me,Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4636

*(Lys(Me)34)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide*	Peptides	Others
(Lys(Me)34)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4614

*(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl)*	Peptides	Others
(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-P3621

Biotinyl-Glucagon (1-29), human, bovine, porcine	GCGR	Metabolic Disease
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .

HY-P4945

Biotinyl-(εAhx)-Gly-Arg-Gly-Asp-Ser	Peptides	Others
Biotinyl-(εAhx)-Gly-Arg-Gly-Asp-Ser is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-P5351

*Hyaluronan-binding peptide, biotin* labeled**	Peptides	Others
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-P5113

*Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide*	Peptides	Others
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4627

*(Lys(Me)29)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)29)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4929

Biotinyl-(Gln1)-Orexin A (human, mouse, rat)	Peptides	Others
Biotinyl-(Gln1)-Orexin A (human, mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4026

*K(biotinyl)-KEDVV-Abu-CS-Abu-SYKK-NH2*	Peptides	Others
K(biotinyl)-KEDVV-Abu-CS-Abu-SYKK-NH2 is a peptide that the primary structure is: Lys(biotinyl)-Lys-Glu-Asp-Val-Val-Abu-Cys-Ser-Abu-Ser-Tyr-Lys-Lys-NH2.

HY-P2551

Biotin-β-Amyloid (17-40)	Amyloid-β	Neurological Disease
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .

HY-P11118

Biotinylated CCDC61 peptide CAPture peptide, biotin-CCDC61 (334-366)	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide specifically isolates intact centrosomes .

HY-P2504

*Syk Kinase Peptide Substrate, Biotin* labeled**	Syk	Others
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.

HY-P3576

Biotin-Gastrin Releasing Peptide, human	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P3623

Biotin-Glucagon-Like Peptide 1 (7-36) amide, human	Fluorescent Dye	Others
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically active peptide. Biotin-Glucagon-Like Peptide 1 (7-36) amide, human can be used for the research of various biochemical studies.

HY-P4078

*(Arg)9 biotin* labeled**	Peptides	Others
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .

HY-P10566

BCOR(498-514), biotinylated	BCL6	Cancer
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an K_D value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .

HY-P10372

pFYN peptide	Src	Cancer
pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .

HY-P4928A

Biotinyl-Amylin (mouse, rat) TFA	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) TFA is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P4620

*(Lys(Me)24)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)24)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4616

*(Lys(Ac)12)-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Ac)12)-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P11461

Biotin-CRF, human, rat Biotin-corticotropin releasing factor	Drug Derivative	Neurological Disease
Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker .

HY-P3574

Biotinyl-Obestatin, rat	Peptides	Others
Biotinyl-Obestatin, rat is a polypeptide.

HY-P4934

Biotinyl-BNP-32 (human)	Peptides	Others
Biotinyl-BNP-32 (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4638

*(Lys(Me)39)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide*	Peptides	Others
(Lys(Me)39)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4925

Biotinyl-(Arg8)-Vasopressin	Peptides	Others
Biotinyl-(Arg8)-Vasopressin is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name		Classification

HY-130809

DBCO-PEG4-Biotin 4 Publications Verification		DBCO
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-173176

4-(2-Azidoethyl)phenol		Azide
4-(2-Azidoethyl)phenol (Ph_N3) is a clickable APEX2 probe. 4-(2-Azidoethyl)phenol (Ph_N3) exhibits reliable labeling ability and enabled two biotinylation routes for downstream analysis .

HY-W110146

*(3aS,4S,6aR)-Biotin-PEG4-Alkyne*		Labeling and Fluorescence Imaging
(3aS,4S,6aR)-Biotin-PEG4-Alkyne is an alkyne-activated biotinylation reagent. (3aS,4S,6aR)-Biotin-PEG4-Alkyne can be reacted with azides via a copper-catalyzed click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection .

HY-130809A

DBCO-PEG1000-Biotin		DBCO
DBCO-PEG1000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809C

DBCO-PEG3400-Biotin		DBCO
DBCO-PEG3400-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809H

DBCO-PEG40000-Biotin		DBCO
DBCO-PEG40000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809I

DBCO-PEG20000-Biotin		DBCO
DBCO-PEG20000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809D

DBCO-PEG5000-Biotin		DBCO
DBCO-PEG5000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809B

DBCO-PEG2000-Biotin		DBCO
DBCO-PEG2000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

HY-130809E

DBCO-PEG10000-Biotin		DBCO
DBCO-PEG10000-Biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .

Cat. No.	Product Name		Classification

HY-W440886

DSPE-PEG3400-Biotin		Pegylated Lipids Fluorescent Lipids
DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.

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