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carbonyl compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1147
    Diethyl maleate
    1 Publications Verification

    Maleic acid diethyl ester

    		 Biochemical Assay Reagents Others
    Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
    Diethyl maleate
  • HY-128429
    trans-​2-​Hexenal

    (E)-2-Hexenal

    		 Environmental Pollutants Biochemical Assay Reagents Fungal Infection
    trans-2-Hexenal ((E)-2-Hexenal) is a volatile compound widely present in fresh plants, vegetables, and fruits, with a unique leafy aroma. trans-2-Hexenal has antifungal activity and can also inhibit the germination of soybean seeds and the growth of seedlings. In addition, trans-2-Hexenal can be used to determine low-molecular-weight carbonyl compounds that are reactive with biological nucleophiles in biological samples .
    trans-​2-​Hexenal
  • HY-20128
    Piperazin-2-one

    		Drug Intermediate Others
    Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .
    Piperazin-2-one
  • HY-40228
    (R)-(+)-tert-Butylsulfinamide

    (R)-2-Methylpropane-2-sulfinamide

    		 Biochemical Assay Reagents Others
    (R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .
    (R)-(+)-tert-Butylsulfinamide
  • HY-W074541
    Girard’s reagent T

    Trimethylacetohydrazideammonium chloride

    		 Biochemical Assay Reagents Others
    Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.
    Girard’s reagent T
  • HY-W273413
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct

    NBD-H

    		 Fluorescent Dye Cancer
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is a fluorescent reagent used for protein labeling .
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct
  • HY-W590569
    Azido-PEG12-amine

    		Biochemical Assay Reagents Others
    Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
    Azido-PEG12-amine
  • HY-D1336
    FAM amine, 6-isomer

    		Fluorescent Dye
    FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
    FAM amine, 6-isomer
  • HY-W010341
    2-Pyridinecarbohydrazide

    		Biochemical Assay Reagents Others
    2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues .
    2-Pyridinecarbohydrazide
  • HY-W017425
    N'-Phenylacetohydrazide

    Phenylhydrazine acetate

    		 Biochemical Assay Reagents Others
    N'-Phenylacetohydrazide consists of a phenyl group attached to the acetylhydrazide functional group via a hydrazine bond. This compound is commonly used as a reagent in organic chemistry for the determination of carbonyl compounds such as aldehydes and ketones.
    N'-Phenylacetohydrazide
  • HY-121206
    (-)-Isopulegol

    		Environmental Pollutants Antibiotic Infection
    (-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research .
    (-)-Isopulegol
  • HY-21983
    O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine

    		Amino Acid Derivatives Others
    O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine is a compound containing both an amino group and a carboxyl group.
    O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine
  • HY-Y1361
    Diethyl D-(-)-tartrate

    D-(-)-Tartaric acid diethyl ester

    		 Biochemical Assay Reagents Drug Intermediate Others
    Diethyl D-(-)-tartrate (D-(-)-Tartaric acid diethyl ester) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diethyl D(-)-tartrate can also react with fatty carbonyl compounds to form bis(sodium carboxylate) types of surfactants, which have good water solubility, strong ability to lower surface tension, and can be easily decomposed under acidic conditions .
    Diethyl D-(-)-tartrate
  • HY-W145090
    4-Dimethylaminopyridine N-oxide

    p-Dimethylaminopyridine N-oxide

    		 Biochemical Assay Reagents Others
    4-Dimethylaminopyridine N-oxide (p-Dimethylaminopyridine N-oxide) is an Efficient Oxidizing Agent for Alkyl Halides .
    4-Dimethylaminopyridine N-oxide
  • HY-21206
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate

    		Drug Intermediate Others
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate is a drug intermediate for synthesis of various active compounds.
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate
  • HY-157445
    CBR1-IN-3

    		NADPH Oxidase Metabolic Disease
    CBR1-IN-3 (compound 13h) is a potent inhibitor of carbonyl reductase 1 (CBR1), with IC50 value of 0.034 μM .
    CBR1-IN-3
  • HY-W063820
    (2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid

    		Drug Intermediate Others
    (2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
    (2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid
  • HY-128429R
    Trans-​2-​Hexenal (Standard)

    (E)-2-Hexenal (Standard)

    		 Fungal Biochemical Assay Reagents Reference Standards Infection
    Trans-​2-​Hexenal (Standard) is the analytical standard of Trans-​2-​Hexenal. This product is intended for research and analytical applications. Trans-​2-​Hexenal can be used for the determination of low-molecular-weight carbonyl compounds which are reactive with biological nucleophiles in biological samples .
    Trans-​2-​Hexenal (Standard)
  • HY-146332
    Collagen-IN-1

    		P-selectin Cardiovascular Disease
    Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
    Collagen-IN-1
  • HY-Z1081
    Monobenzyl Terephthalate

    4-((Benzyloxy)carbonyl)benzoic acid

    		 Drug Intermediate Others
    Monobenzyl Terephthalate (4-((Benzyloxy)carbonyl)benzoic acid) is a drug intermediate for synthesis of various active compounds.
    Monobenzyl Terephthalate
  • HY-D0066
    7-Diethylaminocoumarin-3-carbohydrazide

    DCCH

    		 Fluorescent Dye Others
    7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds .
    7-Diethylaminocoumarin-3-carbohydrazide
  • HY-78192
    N-[N-[(1,1-Dimethylethoxy)carbonyl]-2-methylalanyl]-D-tryptophan

    		Biochemical Assay Reagents Others
    N-[N-[(1,1-Dimethylethoxy)carbonyl]-2-methylalanyl]-D-tryptophan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-[N-[(1,1-Dimethylethoxy)carbonyl]-2-methylalanyl]-D-tryptophan
  • HY-34887
    Acridone-4-carboxylic acid

    		Drug Derivative Others
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM .
    Acridone-4-carboxylic acid
  • HY-43562
    (2S,5S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-phenylpyrrolidine-2-carboxylic acid

    		Drug Intermediate Others
    (2S,5S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-phenylpyrrolidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
    (2S,5S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-phenylpyrrolidine-2-carboxylic acid
  • HY-77826
    4-Chloro-N-methylpicolinamide

    		Epigenetic Reader Domain Cancer
    4-Chloro-N-methylpicolinamide (Compound 3) is a BAZ2A bromodomain inhibitor with a Kd of >500 μM. 4-Chloro-N-methylpicolinamide forms a weak hydrogen bond with the carbonyl oxygen of Pro1817. 4-Chloro-N-methylpicolinamide can be used in the research of invasive prostate cancer .
    4-Chloro-N-methylpicolinamide
  • HY-20128S
    Piperazin-2-one-d6

    		Isotope-Labeled Compounds Drug Intermediate Others
    Piperazin-2-one-d6 is the deuterium labeled Piperazin-2-one (HY-20128). Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .
    Piperazin-2-one-d6
  • HY-151774
    TAMRA hydrazide (6-isomer)

    		Fluorescent Dye Others
    TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .
    TAMRA hydrazide (6-isomer)
  • HY-W190921
    t-Butyl 3-(hydroxypropoxyl)-propanoate

    		Biochemical Assay Reagents Others
    t-Butyl 3-(hydroxypropoxyl)-propanoate contains reactive hydroxyl and t-butyl protected carboxyl moieties. The hydroxyl group can react to further derivatize the compound. The t-butyl carbonyl group can be deprotected under acidic conditions.
    t-Butyl 3-(hydroxypropoxyl)-propanoate
  • HY-161998
    Urease-IN-16

    		Bacterial Urease Others
    Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications .
    Urease-IN-16
  • HY-W101722
    tert-Butyl (9-aminononyl)carbamate

    		PROTAC Linkers Cancer
    tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl (9-aminononyl)carbamate
  • HY-41802
    1-((Benzyloxy)carbonyl)-5-oxopiperidine-2-carboxylic acid

    		Drug Intermediate Others
    1-((Benzyloxy)carbonyl)-5-oxopiperidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
    1-((Benzyloxy)carbonyl)-5-oxopiperidine-2-carboxylic acid
  • HY-N12966
    (±)9,10-DiHODE

    		Others Others
    (±)9,10-DiHODE (compound 4) is a plant oxylipin compound that reduces the carbonyl group of α-ketoalcohols to form adjacent diols. They act as important signaling molecules in plants and play a role in regulating growth and flowering processes .
    (±)9,10-DiHODE
  • HY-132270
    FAM amine, 5-isomer

    		Fluorescent Dye Others
    FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
    FAM amine, 5-isomer
  • HY-151690
    FAM hydrazide, 6-isomer

    		Fluorescent Dye Others
    FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
    FAM hydrazide, 6-isomer
  • HY-132264
    FAM hydrazide, 6-isomer hydrochloride

    		Fluorescent Dye Others
    FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
    FAM hydrazide, 6-isomer hydrochloride
  • HY-42418
    3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-L-proline

    		Drug Intermediate Others
    3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-L-proline is a drug intermediate for synthesis of various active compounds.
    3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-L-proline
  • HY-157447
    CBR1-IN-4

    		Carbonyl Reductase Cancer
    CBR1-IN-4 (Compound 13p) is a human carbonyl reductase 1 (CBR1) inhibitor (IC50=0.09 μM). CBR1-IN-4 can be used in cancer research .
    CBR1-IN-4
  • HY-W800649
    Aminooxy-PEG2-amine hydrochloride

    		Biochemical Assay Reagents Others
    Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
    Aminooxy-PEG2-amine hydrochloride
  • HY-121206R
    (-)-Isopulegol (Standard)

    		Antibiotic Reference Standards Infection
    (-)-Isopulegol (Standard) is the analytical standard of (-)-Isopulegol. This product is intended for research and analytical applications. (-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research .
    (-)-Isopulegol (Standard)
  • HY-W348348
    CbzNH-PEG3-CH2CH2NH2

    		Biochemical Assay Reagents Others
    CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    CbzNH-PEG3-CH2CH2NH2
  • HY-128429S
    trans-2-Hexenal-d2-1

    (E)-2-Hexenal-d2-1

    		 Isotope-Labeled Compounds Fungal Biochemical Assay Reagents Infection
    trans-2-Hexenal-d2-1 is the deuterium labeled trans-2-Hexenal (HY-128429). trans-2-Hexenal ((E)-2-Hexenal) is a volatile compound widely present in fresh plants, vegetables, and fruits, with a unique leafy aroma. trans-2-Hexenal has antifungal activity and can also inhibit the germination of soybean seeds and the growth of seedlings. In addition, trans-2-Hexenal can be used to determine low-molecular-weight carbonyl compounds that are reactive with biological nucleophiles in biological samples .
    trans-2-Hexenal-d2-1
  • HY-W697750
    trans-2-Methyl-2-butenal

    Tiglaldehyde

    		 Biochemical Assay Reagents Cancer
    trans-2-Methyl-2-butenal (Tiglaldehyde) is an adduct former that can be found in cigarette smoke, and very weakly inhibits growth of cancer cells and normal mouse cells. trans-2-Methyl-2-butenal forms adducts with glutathione (GSH) via Michael addition.trans-2-Methyl-2-butenal is an α,β-unsaturated carbonyl compound .
    trans-2-Methyl-2-butenal
  • HY-W150273
    6-Aminocoumarin hydrochloride

    		Biochemical Assay Reagents Others
    6-Aminocoumarin hydrochloride is a coumarin dye, which belongs to the donor-acceptor compounds as it contains a donor amine group and an acceptor carbonyl group .
    6-Aminocoumarin hydrochloride
  • HY-N13179
    Wilforic acid A

    		Others Others
    Wilforic acid A is a triterpene compound that can be isolated from the Tripterygium wilfordii. Wilforic acid A shows a hydroxyl absorption band at 3402 cm -1 and a carbonyl absorption band at 1702 cm -1 .
    Wilforic acid A
  • HY-W190904
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane

    		Biochemical Assay Reagents Others
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane has a TBDMS, acid labile protecting group. TBDMS is used for the protection of alcohol groups. The primary amine is able to react with carboxylic acids, active NHS esters and other carbonyl compounds.
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane
  • HY-W1113139
    H2N-PEG4-C3-OH

    		Biochemical Assay Reagents Others
    H2N-PEG4-C3-OH is a PEG linker with a terminal amino group that can react with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Hydroxyl group can react with a variety of functional groups. PEG spacer improves the compound's aqueous solubility.
    H2N-PEG4-C3-OH

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