3 Results for "

complement cascade components

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "complement cascade components" in MCE Product Catalog:

Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Claseprubart (DNTH103) is an inhibitor targeting C1s of the complement system and an inhibitor of the C1 component of the complement cascade. Claseprubart is in phase 2 clinical evaluation. Claseprubart has application potential in research related to multifocal motor neuropathy and generalized myasthenia gravis .
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Cat. No.: HY-P10227
CAS No.: 2040964-58-5
Synonyms: ONL-1204
Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma .
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Cat. No.: HY-P991665
Synonyms: OBT357NF; OBT357

Research Areas:  

Cancer

MEN1112 (OBT357NF; OBT357) is a defucosylated humanized monoclonal antibody targeting Bst1/CD157, with an EC50 of 0.4 nM. MEN1112 binds to Bst1/CD157 on acute myeloid leukemia cells, triggers slow antigen internalization, induces antibody-dependent cell-mediated cytotoxicity, and mediates the lysis of acute myeloid leukemia cells and blasts. MEN1112 is applicable for research related to acute myeloid leukemia .
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