2 Results for "

durable memory

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "durable memory" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-148029
CAS No.: 2553413-93-5
Purity:  98.16%
Synonyms: TAK-676
Target:  

STING

Research Areas:  

Cancer

Dazostinag disodium (TAK-676) is an agonist of STING, triggering the activation of STING signaling pathway and type I interferons. Dazostinag disodium is also a modulator of immune system, resulting complete regressions and durable memory T-cell immunity. Dazostinag disodium promotes durable IFN-dependent antitumor immunity .
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Cat. No.: HY-159643
CAS No.: 2628486-22-4
NDI-101150 is an orally active, potent and selective hematopoietic progenitor cell kinase 1 (HPK1) inhibitor with an IC50 of 0.7 nM. NDI-101150 blocks HPK1-mediated negative regulation of immune receptor signaling, inhibits immunosuppression of T cell activation, enhances antigen-specific antibody production and augments B-cell activation. NDI-101150 inhibits tumor growth in syngeneic tumor models, establishes durable antitumor immune memory, and synergizes with anti-PD1 to enhance exhausted T cell activity and drive tumor regressions. NDI-101150 can be used for the research of cancer, such as breast cancer and colon cancer .
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