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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
eIF4G
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "eIF4G" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-19831
CAS No.: 315706-13-9
Research Areas:
4EGI-1 is an inhibitor of eIF4E/eIF4G interaction, with a Kd of 25 μM against eIF4E binding.
5
5 Cited Publications
Research Areas:
4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.
3
Research Areas:
SBI-0640756 (SBI-756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex.
1
1 Cited Publications
Cat. No.: HY-159059
Purity: 41.20%
Cat. No.: HY-19831A
CAS No.: 901787-88-0
Research Areas:
(Z)-4EGI-1 is the Z-isomer of 4EGI-1 and is an inhibitor of eIF4E/eIF4G interaction and of translation initiation. (Z)-4EGI-1 effectively binds to eIF4E with an IC50 of 43.5 μM and a Kd value of 8.74 μM. (Z)-4EGI-1 has anticancer activity .
Cat. No.: HY-176288
Research Areas:
eIF4E/eIF4G PPI-IN-1 is an eIF4E/eIF4G interaction inhibitor with a KD of 20.2 μM for eIF4E protein. eIF4E/eIF4G PPI-IN-1 plays an antitumor role in multiple modes of action including regulating the activity of eIF4E by inhibiting the Ras/MAPK/eIF4E signaling pathway, apoptosis and cell migration. eIF4E/eIF4G PPI-IN-1 suppresses the growth of HepG2 xenografts in nude mice and was relatively nontoxic to mice .
Cat. No.: HY-RS04281
Target:
Research Areas:
EIF4G1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04282
Target:
Research Areas:
EIF4G2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04283
Target:
Research Areas:
EIF4G3 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19254
Target:
Research Areas:
Eif4g1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4g1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25743
Target:
Research Areas:
Eif4g1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4g1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705694
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: eIF 4 gamma 1; eIF 4G 1; eIF 4G1; eIF-4-gamma 1; eIF4G; Eukaryotic translation initiation factor 4 gamma 1
Cat. No.: HY-100733R
CAS No.: 432499-63-3
Research Areas:
4E2RCat (Standard) is the analytical standard of 4E2RCat (HY-100733). This product is intended for research and analytical applications. 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.
Cat. No.: HY-164524
CAS No.: 1321827-45-5
Research Areas:
SBI-0640726 is an eIF4G1 inhibitor with antiproliferative activity in melanoma. SBI-0640726 disrupts the eIF4F translation initiation complex by inhibiting AKT and NF-kB signaling pathways. SBI-0640726 inhibits the growth of NRAS and BRAF mutant melanoma in vitro .
Cat. No.: HY-182704
CAS No.: 832680-32-7
Synonyms: SBI-1275844
Research Areas:
SBI-5844 (SBI-1275844) is a eIF4F complex inhibitor and antiviral agent. SBI-5844 disrupts the assembly of the eIF4F complex and blocks the interaction between eIF4E and eIF4G. SBI-5844 inhibits the synthesis of HCoV-OC43 nucleocapsid protein and reduces the levels of HCoV-OC43 RNA and total protein. SBI-5844 can be used in studies related to human coronavirus OC43 (HCoV-OC43) infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
