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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
endothelin-B receptor
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "endothelin-B receptor" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
A-192621, a chemical probe, is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. The selectivity of A-192621 is 636-fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A-192621 promotes apoptosis in PASMCs. A-192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level .
Synonyms: SRTX-c
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Research Areas:
Cat. No.: HY-106337
CAS No.: 188186-61-0
Target:
Research Areas:
SB 247083 is a selective, competitive and orally active endothelin-A receptor antagonist with a Ki of 0.41 nM. SB 247083 shows a Ki of 467 nM to endothelin-B receptor. SB 247083 shows a Kb of 3.5 nM for ET-1-induced contraction of rat aorta. SB 247083 can be used for the research of cardiovascular disease .
Cat. No.: HY-P2057
CAS No.: 143037-36-9
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Research Areas:
Cat. No.: HY-P1018
CAS No.: 144602-02-8
Target:
Research Areas:
Cat. No.: HY-147417AS
CAS No.: 2364572-10-9
Research Areas:
Vodudeutentan sodium is a deuterated endothelin B receptor (ETBR) antagonist with no activity against human type A endothelin receptor (ETA). Vodudeutentan sodium can be incorporated into a controlled systemic release delivery system and can also be selectively combined with an additional antineoplastic agent. Vodudeutentan sodium is applicable to the research of urothelial carcinoma, bladder cancer and renal cell carcinoma .
Cat. No.: HY-P83206A
Synonyms: GPR37; Probable G-protein coupled receptor 37; endothelin B receptor-like protein 1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor; PAELR
Cat. No.: HY-P76376
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPR37; endothelin B receptor-Like Protein 1; G Protein-Coupled receptor 37; Prosaposin receptor GPR37; PAELR; ETBR-LP-1; HET(B)R-LP; Probable G-Protein Coupled receptor 37; EDNRBL; endothelin receptor Type B-Like; G Protein-Coupled receptor 37 (endothelin
Species:
Human
Source:
HEK293
Cat. No.: HY-P74180
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EDNRB; ETRB; Prev. HSCR2; Hirschsprung Disease 2; Prev. HSCR; ABCDS; endothelin receptor Non-Selective Type; ETB1; ETB; ETBR; ET-BR; WS4A; ET-B; endothelin receptor Type B; endothelin receptor Subtype B1
Species:
Human
Source:
HEK293
Cat. No.: HY-P74181
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: EDNRB; ETRB; Prev. HSCR2; Hirschsprung Disease 2; Prev. HSCR; ABCDS; endothelin receptor Non-Selective Type; ETB1; ETB; ETBR; ET-BR; WS4A; ET-B; endothelin receptor Type B; endothelin receptor Subtype B1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
