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ether lipid

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By Targets:	Akt (1) Apoptosis (2) Biochemical Assay Reagents (4) DNA/RNA Synthesis (1) Drug Intermediate (1) Endogenous Metabolite (1) Environmental Pollutants (3) HIV (2) Liposome (2) Platelet-activating Factor Receptor (PAFR) (1) Reference Standards (1) TNF Receptor (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (2) Metabolic Disease (5)
Oligonucleotides:	Pegylated Lipids (1) Cationic Lipids (1) Phospholipids (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1883

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant 20+ Cited Publications	Environmental Pollutants Biochemical Assay Reagents Apoptosis	Infection Cancer
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-Y1883A

Polyethylene glycol mono(4-tert-octylphenyl) ether 20+ Cited Publications	Environmental Pollutants Biochemical Assay Reagents	Infection Cancer
Polyethylene glycol mono(4-tert-octylphenyl) ether is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-153910

AGPS-IN-1	Others	Cancer
AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells .

HY-108610

(R)-Edelfosine (R)-ET-18-OCH3	HIV	Infection Cancer
(R)-Edelfosine ((R)-ET-18-OCH3) is a ether lipid analog with anti-HIV and antineoplastic activity .

HY-W250183B

Polyoxyethylene (20) stearyl ether Polyethylene glycol octadecyl ether (n～20)	Environmental Pollutants Liposome	Others
Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles .

HY-108610C

(S)-Edelfosine (S)-ET-18-OCH3	Apoptosis	Cancer
(S)-Edelfosine ((S)-ET-18-OCH3) is the (S)-enantiomer of Edelfosine (ET-18-OCH3) (HY-108610C). Edelfosine is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor .

HY-W923483

C16-18:1 PC 1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine	Platelet-activating Factor Receptor (PAFR) Endogenous Metabolite	Cardiovascular Disease
C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.

HY-135801

Arachidonyl alcohol	Drug Intermediate	Metabolic Disease
Arachidonyl alcohol is a long-chain primary fatty alcohol. Arachidonyl alcohol is used as a substrate for the production of several ether lipids possessing beneficial functions .

HY-134070

2-O-Methyl PAF C-16 ET-18-O-OCH3	TNF Receptor	Inflammation/Immunology
2-O-Methyl PAF C-16 (ET-18-O-OCH3), a structural analog of the mediator of inflammation platelet-activating factor (PAF), is a cytotoxic ether lipid. 2-O-Methyl PAF C-16 stimulates TNF-α release in murine macrophages .

HY-157696

18:0 Diether PC 1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents	Others
18:0 Diether PC (1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine) is a glycerophospholipid that can be used as a nonhydrolizable ether lipid in calcein-containing vesicles .

HY-179788

18:1 Dimethylacetal	Others	Metabolic Disease
18:1 Dimethylacetal is an ether lipid. Ether lipids are mainly found in cell membranes.

HY-179785

18:0 Dimethylacetal	Others	Metabolic Disease
18:0 Dimethylacetal is an ether lipid. Ether lipids are mainly found in cell membranes.

HY-179750

1,1-Dimethoxyhexadecane	Biochemical Assay Reagents
1,1-Dimethoxyhexadecane is an ether lipid. Ether lipids are mainly found in cell membranes.

HY-N16079

C18(Plasm)-18:1 PC	Others	Metabolic Disease
C18(Plasm)-18:1 PC is an ether lipid. Ether lipids are mainly found in cell membranes.

HY-W1130450

Lipid ND-O1	Liposome	Inflammation/Immunology
Lipid ND-O1 is an ether-containing ionizable cationic lipid pK_a of 6.6. Lipid ND-O1 can be used to generate lipid nanoparticles (LNPs) for siRNA delivery in vitro and in vivo. Lipid ND-O1 LNPs can be studied in research on hepatic fibrosis .

HY-119134

PX-316	Akt	Cancer
PX-316 is an Akt inhibitor. PX-316 can phosphorylate Akt, but does not inhibit the phosphorylation of PDK1 or PKC. PX-316 uniquely increases the expression of a group of mitochondrial-related genes. PX-316 can be used for the study of colon cancer and breast cancer .

HY-108610R

(R)-Edelfosine (Standard) (R)-ET-18-OCH3 (Standard)	Reference Standards HIV	Infection Cancer
(R)-Edelfosine (Standard) is the analytical standard of (R)-Edelfosine (HY-108610). This product is intended for research and analytical applications. (R)-Edelfosine ((R)-ET-18-OCH3) is a ether lipid analog with anti-HIV and antineoplastic activity .

HY-W565665

(S)-HPMPA	DNA/RNA Synthesis Others	Infection
(S)-HPMPA is an antiviral agent. (S)-HPMPA can bind to and interfere with viral DNA polymerase activity, thereby inhibiting viral DNA synthesis. (S)-HPMPA can be used for the study of DNA viruses .

Cat. No.	Product Name	Type

HY-Y1883

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant 20+ Cited Publications	Biochemical Assay Reagents
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant

20+ Cited Publications

Biochemical Assay Reagents

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-W250183B

Polyoxyethylene (20) stearyl ether Polyethylene glycol octadecyl ether (n～20)	Biochemical Assay Reagents
Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles .

HY-157696

18:0 Diether PC 1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents
18:0 Diether PC (1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine) is a glycerophospholipid that can be used as a nonhydrolizable ether lipid in calcein-containing vesicles .

Cat. No.	Product Name		Classification

HY-W250183B

Polyoxyethylene (20) stearyl ether Polyethylene glycol octadecyl ether (n～20)		Pegylated Lipids
Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles .

HY-157696

18:0 Diether PC 1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine		Phospholipids
18:0 Diether PC (1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine) is a glycerophospholipid that can be used as a nonhydrolizable ether lipid in calcein-containing vesicles .

HY-157682

16:0-18:1 Diether PE		Phospholipids
16:0-18:1 Diether PE is an ether lipid. Ether lipids are mainly found in cell membranes.

HY-179829

DSDMA		Cationic Lipids
DSDMA is an ionizable ether lipid for RNA and vaccine delivery.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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