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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
excited-state proton transfer
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "excited-state proton transfer" in MCE Product Catalog:
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Cat. No.: HY-D0077
CAS No.: 195136-58-4
Synonyms: Oregon green 488
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2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
Cat. No.: HY-W140203
CAS No.: 2963-66-8
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2-(2′-Hydroxyphenyl) benzimidazole is the most extensively studied excited-state intramolecular proton transfer (ESIPT) molecule, exhibiting normal and tautomer emissions. 2-(2′-Hydroxyphenyl) benzimidazole has been applied as a fluorescent probe in various systems .
Cat. No.: HY-N16571
CAS No.: 65602-55-3
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Cat. No.: HY-D2286
Synonyms: Furro ER (Standard); NSC 9586 (Standard); Nako TRB (Standard)
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Cat. No.: HY-Y1309S1
CAS No.: 124251-84-9
Synonyms: Furro ER-d7; NSC 9586-d7; Nako TRB-d7
Cat. No.: HY-Y1309S
CAS No.: 207569-03-7
Synonyms: Furro ER-d8; NSC 9586-d8; Nako TRB-d8
Cat. No.: HY-D3150
CAS No.: 905306-19-6
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di-SFA is a fluorescent probe used to measure transmembrane potential (Vm) across the plasma membrane. di-SFA contains a 3-hydroxychromone fluorophore that undergoes excited-state intramolecular proton transfer (ESIPT), producing dual emission from the normal (N*) and tautomeric (T*) states. di-SFA inserts deeply into the hydrophobic region of lipid bilayers. The sulfonate groups give di-SFA a double negative charge in aqueous media. Ratiometric measurements are performed in lipid vesicles using Ex/Em = 450/527 nm and Ex/Em = 450/605 nm.
Cat. No.: HY-D3067
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ASSI-Leu is a novel AIE fluorescent probe based on an asymmetric tetraaryl imidazole skeleton, which can be used for ratiometric imaging detection of endogenous leucine aminopeptidase. ASSI-Leu contains an L-leucine-based recognition group that blocks the excited-state intramolecular proton transfer (ESIPT) in its 2-(2'-hydroxyphenyl) benzothiazole (HBT) skeleton, thereby generating an enol-form emission signal at Ex/Em = 365/417 nm. ASSI-Leu undergoes cleavage of the L-leucine group mediated by LAP to form ASSI-OH, which further activates aggregation-induced emission (AIE) and ESIPT, generating a keto-form emission signal at Ex/Em = 365/554 nm and producing a ratiometric fluorescent signal. ASSI-Leu enables real-time tracking of LAP in cancer cells and zebrafish models .\n
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
