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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
glucose binding site
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "glucose binding site" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-N2593
CAS No.: 32507-66-7
Cat. No.: HY-124529
CAS No.: 37116-80-6
Category:
Human Gut Microbiota Metabolites Conocephalum conicum (L.) Dumort. Phenols Polyphenols Plants Other Families Extract Endogenous metabolite
Target:
Synonyms: ZGN-1061
Target:
연구분야:
Aclimostat (ZGN-1061) is a methionine aminopeptidase 2 (MetAP2) inhibitor. Aclimostat exhibits anti-obesity, anti-diabetic and ovarian cancer-related activities, and does not readily distribute to the central nervous system. Aclimostat acts on the active site of MetAP2 via irreversible covalent binding, and blocks enzyme activity through interactions with His231 and His339. Aclimostat regulates gene expression, reduces fat mass, plasma glucose, insulin levels, LDL-C, hs-CRP and leptin levels, while increasing adiponectin levels. Aclimostat can be used in research related to type 2 diabetes, overweight, obesity and ovarian cancer .
Cat. No.: HY-N7433
CAS No.: 13224-99-2
Synonyms: Ethylidene-glucose
Target:
Cat. No.: HY-P0262
CAS No.: 138579-66-5
Target:
Cat. No.: HY-N7433R
CAS No.: 13224-99-2
Synonyms: Ethylidene-glucose (Standard)
Category:
Cat. No.: HY-N2593R
CAS No.: 32507-66-7
Cat. No.: HY-183878
CAS No.: 71431-46-4
Target:
연구분야:
Zincov is an orally active hydroxamic acid derivative and bacterial metalloproteinase inhibitor. Zincov blocks chloride ion binding by binding to the active site of thermolysin, thereby inhibiting the hydrolysis and blood coagulation reactions catalyzed by this enzyme. Meanwhile, Zincov attenuates cytotoxicity, prevents protein degradation and ZO-1 rearrangement without affecting the functions of other common proteases. Zincov exhibits blood glucose-regulating and antioxidant activities; it reduces blood glucose levels and increases liver dry weight in diabetic rats, but elevates blood glucose levels in normal rats. Zincov is widely used in studies related to cholera and diabetes .
Cat. No.: HY-D3030
Target:
Concanavalin A-FITC is a FITC (HY-66019)-labeled Concanavalin A (HY-P2149). Concanavalin A-FITC is a fluorescent probe and dye used to detect cell surface sugar-binding sites, oligosaccharide changes and track cell localization. Concanavalin A-FITC binds to α-D-glucose, α-D-mannose and mannose residues on cell surface glycoproteins, glycolipids and glycoconjugates, with fluorescence signals provided by FITC. Concanavalin A-FITC accumulates in perinuclear endoplasmic reticulum-related regions via endocytosis and localizes to mitochondria. The excitation/emission wavelength of Concanavalin A-FITC is Ex/Em = 488/>510 nm, and its emitted green fluorescence can be collected with a 530/30 nm filter during flow cytometry detection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
