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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
human CCR8
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "human CCR8" in MCE Product Catalog:
Cat. No.: HY-P990914
CAS No.: 2865822-82-6
Synonyms: GS-1811; JTX-1811
Target:
Research Areas:
Cat. No.: HY-P991061
CAS No.: 3024486-14-1
Synonyms: CHS-114; SRF-114
Tagmokitug (CHS-114; SRF-114) is a fully human IgG1 antibody targeting CCR8. Tagmokitug selectively binds to human CCR8 (Kd = 502 pM) and mediates the death of CCR8-expressing cells via antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. Tagmokitug selectively eliminates intratumoral regulatory T cells, induces tumor growth inhibition, remodels the tumor immune microenvironment, and promotes the differentiation of cytotoxic CD8 + T cell subsets. Tagmokitug can be used for the research of solid tumors .
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CCR8 antagonist 1 (Compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM. CCR8 antagonist 1 has high safety and metabolic stability. CCR8 antagonist 1 can be used to study diseases such as asthma and multiple sclerosis .
Cat. No.: HY-P990904
CAS No.: 2837169-12-5
Synonyms: PR-1925514
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Cat. No.: HY-P990908
CAS No.: 2851855-89-3
Synonyms: LM-108
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Cat. No.: HY-174741
Target:
Research Areas:
Human CCR8 mRNA encodes the human C-C motif chemokine receptor 8 (CCR8) protein, a member of the beta chemokine receptor family. CCR8 plays a role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.
Cat. No.: HY-RS02169
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CCR8 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153669
CAS No.: 935262-95-6
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SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma .
Cat. No.: HY-P991135
CAS No.: 2999644-88-9
Synonyms: RO-7502175; RG-6411
Cat. No.: HY-160647
CAS No.: 912463-57-1
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CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC50 value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability .
Cat. No.: HY-P991942
Synonyms: BAY3375968; TPP-23411
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Cat. No.: HY-P991942A
Synonyms: BAY3375968 (FUT8-KO); TPP-23411 (FUT8-KO)
Lanerkitug (FUT8-KO) (BAY3375968 (FUT8-KO)) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Lanerkitug (HY-P991942) selectively depletes human CCR8+Tregs via antibody dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP). Lanerkitug can be used in the research of solid tumors .
Cat. No.: HY-P992365
Cat. No.: HY-P77882
Purity: ≥ 95%, as determined by HPLC.
Synonyms: CCR8; Chemokine Receptor-Like 1; Prev. CMKBRL2; GPRCY6; Prev. CMKBR8; CCR-8; TER1; CKRL1; C-C Chemokine Receptor Type 8; Chemokine (C-C) Receptor-Like 2; GPR-CY6; CC-Chemokine Receptor Chemr1; CKR-L1; Chemokine (C-C) Receptor 8; CDw198; CC Chemokine Recep
Species:
Human
Source:
HEK293
Cat. No.: HY-P700543
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCR8; Chemokine Receptor-Like 1; Prev. CMKBRL2; GPRCY6; Prev. CMKBR8; CCR-8; TER1; CKRL1; C-C Chemokine Receptor Type 8; Chemokine (C-C) Receptor-Like 2; GPR-CY6; CC-Chemokine Receptor Chemr1; CKR-L1; Chemokine (C-C) Receptor 8; CDw198; CC Chemokine Recep
Species:
Human
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
