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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
human GCGR
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "human GCGR" in MCE Product Catalog:
3
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Cat. No.: HY-P3375
CAS No.: 2259884-03-0
Synonyms: IBI-362; LY-3305677; OXM-3
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Cat. No.: HY-P99357
CAS No.: 1452387-69-7
Synonyms: REGN1193; Anti-GCGR Reference Antibody (crotedumab)
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NNC-0640 is an effective negative allosteric modulator (NAM) of the human glucagon receptor (GCGR), with an IC50 value of 69.2 nM. NNC-0640 holds potential for research in the field of diabetes .
Cat. No.: HY-P3375A
Synonyms: IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA
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Cat. No.: HY-P10031
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Cat. No.: HY-P4389
CAS No.: 1037751-81-7
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(Asp28)-Glucagon (1-29) (human, rat, porcine) is a glucagon analog and a GCGR agonist, with the Asn at position 28 replaced by Asp. (Asp28)-Glucagon (1-29) (human, rat, porcine) activates GCGR-mediated cAMP signaling, with EC50 values of 0.067 nM and 0.09 nM, respectively, and an EC50 of 7.99 nM for GLP-1R. (Asp28)-Glucagon (1-29) (human, rat, porcine) is useful for studies on glucagon receptor signaling, carbohydrate metabolism, and hypoglycemia .
Cat. No.: HY-P10031A
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Cat. No.: HY-P3506CP
CAS No.: 2381089-83-2
Synonyms: LY3437943 (crude)
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Cat. No.: HY-RS05324
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GCGR Human Pre-designed siRNA Set A contains three designed siRNAs for GCGR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P12143
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GCGR/GLP‐1 receptor agonist P1 is a dual GCGR/GLP-1R agonist. GCGR/GLP‐1 receptor agonist P1 activates human GCGR in vitro and induces the cyclic adenosine monophosphate (cAMP) signaling pathway. GCGR/GLP‐1 receptor agonist P1 is applicable to research related to type 2 diabetes and obesity .
Cat. No.: HY-P703992
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P704626
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P704627
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P703987
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P705157
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P700411
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P3506S
Synonyms: LY3437943, Pro40(13C5,15N) TFA
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Retatrutide, Pro40( 13C5, 15N) (LY3437943, Pro40( 13C5, 15N) TFA) is the 13C, 15N-labeled Retatrutide (HY-P3506). Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
