7 Results for "

human monocytic leukemia

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "human monocytic leukemia" in MCE Product Catalog:

  • Categories Recommended:
    More
10
10 Cited Publications
Cat. No.: HY-19619
CAS No.: 200933-14-8
Target:  

Phospholipase Apoptosis

Research Areas:  

Cancer

m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-111866
CAS No.: 1801547-16-9
Purity:  99.89%
Research Areas:  

Metabolic Disease Cancer

PROTAC RIPK degrader-2 is a non-peptidic PROTAC degrader targeting RIPK2, with a DC50 of 1.5 nM. PROTAC RIPK degrader-2 recruits VHL or cereblon E3 ubiquitin ligases, induces ubiquitination and proteasomal degradation of RIPK2, acts via substoichiometric catalysis, and inhibits downstream pro-inflammatory signaling pathways. PROTAC RIPK degrader-2 inhibits the NOD2/RIPK2 pathway and suppresses MDP (HY-127090)-stimulated TNFα release in human whole blood. PROTAC RIPK degrader-2 can be used in studies related to acute monocytic leukemia and glucose metabolism .
loading...
    loading...
Cat. No.: HY-N8390
CAS No.: 168293-15-0
3-Epidehydropachymic acid, a lanostane triterpenoid, shows totoxicity effect against human acute monocytic leukemia cell line THP-1 (IC50=52.51 μM) .
loading...
    loading...
Cat. No.: HY-19619R
CAS No.: 200933-14-8
Target:  

Phospholipase Apoptosis

Research Areas:  

Cancer

m-3M3FBS (Standard) is the analytical standard of m-3M3FBS. This product is intended for research and analytical applications. m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis .
loading...
    loading...
Cat. No.: HY-N20639
CAS No.: 464-71-1
Synonyms: 3-Deoxycaryoptinol
Clerodin (3-Deoxycaryoptinol) is a natural diterpenoid compound that can be isolated from traditional Chinese medicinal plants such as Clerodendrum infortunatum. Clerodin exhibits caspase-3 regulation, apoptosis induction, cell cycle arrest, ROS induction and glutathione depletion effects, along with anti-cancer and antifeedant activities. It shows selective cytotoxicity against leukemia cells and breast cancer cells, but has no obvious toxicity to normal human blood cells and lymphocytes. Clerodin also reduces the feeding behavior of Helicoverpa armigera larvae on cabbage leaf discs, but has no significant contact toxicity to these larvae. Clerodin can be used in research related to acute monocytic leukemia and human breast cancer .
loading...
    loading...
Cat. No.: HY-P704206
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KAT6B; K(Lysine) Acetyltransferase 6B; Prev. MYST4; MOZ-Related Factor; MOZ2; ZC2HC6B; Querkopf; MYST-4; Morf; Histone Acetyltransferase MYST4; Qkf; Histone Acetyltransferase MORF; MYST Histone Acetyltransferase (monocytic leukemia) 4; Histone Acetyltrans
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-P703234
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT6A; Histone Acetyltransferase KAT6A; Prev. MYST3; Zinc Finger Protein 220; Prev. RUNXBP2; ZC2HC6A; Prev. ZNF220; MYST-3; MOZ; Runt-Related Transcription Factor-Binding Protein 2; monocytic leukemia Zinc Finger Protein; Histone Acetyltransferase MYST3;
Species:  
Human
Source:  
E. coli
loading...
    loading...