5 Results for "

hyaluronidase inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "hyaluronidase inhibitor" in MCE Product Catalog:

Trifolirhizin
Trifolirhizin
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Cat. No.: HY-N0616
CAS No.: 6807-83-6
Category:  

Flavonoids Leguminosae Extract Plants Trifolium pratense Linn. Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology Other Flavonoids Cancer

Target:  

Tyrosinase TNF Receptor Bacterial Apoptosis Autophagy AMPK mTOR ERK NF-κB

Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC50 value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .
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Lunularic acid
Lunularic acid
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Cat. No.: HY-124504
CAS No.: 23255-59-6
Category:  

Marchantia alpestris Phenols Polyphenols Plants Marchantiaceae Extract

Target:  

Endogenous Metabolite

Lunularic acid is a dihydrostilbene compound with anti-hyaluronidase activity (IC50: 0.13 nM). Lunularic acid can be used as an endogenous growth inhibitor in liverworts, replacing the function of abscisic acid in higher plants .
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Nyasol
Nyasol
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Cat. No.: HY-138050
CAS No.: 96895-25-9
Synonyms: (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol
Category:  

Phenols Polyphenols Hypoxis angustifolia Lam. Plants Asparagaceae Extract

Target:  

NO Synthase Bacterial Fungal Parasite Leukotriene Receptor

Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .
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1,2,4,6-Tetra-O-galloyl-β-D-glucose
1,2,4,6-Tetra-O-galloyl-β-D-glucose
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Cat. No.: HY-N15572
CAS No.: 84297-49-4
Category:  

Phenols Polyphenols Plants Eucalyptus globulus Labill. Myrtaceae Extract

Target:  

Amyloid-β HSV Cholinesterase (ChE) Tyrosinase

1,2,4,6-Tetra-O-galloyl-β-D-glucose is an acetylcholinesterase inhibitor with an IC50 of 1.5 μM against human targets. 1,2,4,6-Tetra-O-galloyl-β-D-glucose inhibits the aggregation of amyloid-β. 1,2,4,6-Tetra-O-galloyl-β-D-glucose exhibits anti-herpesvirus activity against both HSV-1 and HSV-2 in vitro. 1,2,4,6-Tetra-O-galloyl-β-D-glucose possesses superoxide dismutase-like antioxidant activity, and also inhibits tyrosinase and hyaluronidase. 1,2,4,6-Tetra-O-galloyl-β-D-glucose can be used in studies related to Alzheimer's disease, herpesvirus infection and antioxidation .
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Monardic acid A
Monardic acid A
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Cat. No.: HY-N16715
CAS No.: 1607436-76-9
Category:  

Lignans Boraginaceae Extract Phenylpropanoids Plants Pulmonaria officinalis L.

Target:  

Cholinesterase (ChE)

Monardic acid A is a selective inhibitor of AChE, with an IC50 of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases .
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