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Results for "

hyphae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (2) Calcineurin (1) Cytochrome P450 (1) Environmental Pollutants (2) Fungal (17) Herbicide (1) HIV (1) Interleukin Related (3) Isotope-Labeled Compounds (1) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) Parasite (3) PKC (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) Succinate Dehydrogenase (1)
By Research Areas:	Infection (18) Inflammation/Immunology (5) Metabolic Disease (5)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1858

Isoprothiolane 2 Publications Verification	Environmental Pollutants Parasite Fungal Interleukin Related	Infection Metabolic Disease Inflammation/Immunology
Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

HY-N7107

Fenchyl alcohol	Environmental Pollutants Fungal	Infection Metabolic Disease
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-W782599

Senkyunolide B	Fungal PKC Calcineurin	Infection
Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes .

HY-120921

Zoxamide RH-7281	Fungal Microtubule/Tubulin	Infection
Zoxamide (RH-7281) is an oomycete Fungicide and covalent β-tubulin inhibitor. RH-7281 inhibits the assembly of tubulin into microtubules in vitro. Zoxamide binds covalently to β-tubulin, disrupting microtubule assembly and the cytoskeleton. Zoxamide blocks nuclear division in germinated hyphae of Phytophthora capsici and inhibits hyphal growth of Phytophthora capsici .

HY-156090

PK-10	Mitochondrial Metabolism Fungal	Infection
PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction .

HY-151284

Antifungal agent 38	Bacterial Fungal	Infection
Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents .

HY-159481

SDH-IN-17	Succinate Dehydrogenase Fungal	Infection Inflammation/Immunology
SDH-IN-17 (compound C32), a hydrazide-containing flavonol derivative, is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 8.42 μM. SDH-IN-17 can occupy the active site and form strong interactions with the key residues of SDH. SDH-IN-17 exhibits antifungal activity against Rhizoctonia solani (EC₅₀=0.170 μg/mL). SDH-IN-17 disrupts the normal growth of hyphae by affecting the structural integrity of the cell membrane and cellular respiration. SDH-IN-17 has the potential for plant disease control research .

HY-N7107R

Fenchyl alcohol (Standard)	Reference Standards Fungal	Infection Metabolic Disease
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-147970

Antifungal agent 34	Fungal	Infection
Antifungal agent 34 (compound 6i) is a potent antifungal agent. Antifungal agent 34 shows a potent antifungal activity against Candida albicans, with a MIC of 4 µg/mL. Antifungal agent 34 shows significant inhibition on Candida albicans hyphae and biofilm development. Antifungal agent 34 exhibits no cytotoxicity to mammalian cells .

HY-163397

Antibacterial agent 196	Fungal	Infection
Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows antifungal activity, with the EC₅₀ of 0.46 μg/mL against Rhizoctonia solani .

HY-B1858S

Isoprothiolane-d4	Isotope-Labeled Compounds Fungal Interleukin Related Parasite	Infection Metabolic Disease Inflammation/Immunology
Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

HY-B1858R

Isoprothiolane (Standard)	Reference Standards Fungal Interleukin Related Parasite	Infection Metabolic Disease Inflammation/Immunology
Isoprothiolane (Standard) is the analytical standard of Isoprothiolane (HY-B1858). This product is intended for research and analytical applications. Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

HY-151280

Antifungal agent 37	Bacterial Fungal	Infection
Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity .

HY-159585

CYP51-IN-20	Cytochrome P450 Fungal	Infection
CYP51-IN-20 (compound 5b) is an inhibitor of CYP51 and has antifungal activity. CYP51-IN-20 has a significant inhibitory effect on Candida albicans ATCC 10231, downregulates ERG11 (Cyp51) gene expression, and significantly reduces the yeast-to-hyphae morphological transition. CYP51-IN-20 can synergize with Voriconazole (HY-76200) to occupy the entire CYP51 binding site and exert a synergistic inhibitory effect in the Glechoma moth model .

HY-174388

Antifungal agent 134	Fungal Herbicide Reactive Oxygen Species (ROS)	Infection
Antifungal agent 134 (Compound B13) is an antifungal agent with EC₅₀s of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL for Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata, respectively. Antifungal agent 134 can disrupt the cell membrane and mitochondria of the hyphae, leading to significant ROS accumulation. Antifungal agent 134 also has significant herbicidal activities against field weeds, such as Amaranthus retroflexus L and Abutilon theophrasti Medicus. Antifungal agent 134 can be used for crop diseases and field weeds research .

HY-181492

Antifungal agent 155 hydrochloride	Fungal	Infection Inflammation/Immunology
Antifungal agent 155 hydrochloride is an antifungal agent. Antifungal agent 155 hydrochloride induces bent, twisted, abnormally swollen hyphae, compromises fungal hyphal plasma membrane integrity, and triggers fungal cell death. Antifungal agent 155 hydrochloride can be used for the research of fusarium keratitis .

HY-170378

Laccase-IN-5	Fungal	Infection
Laccase-IN-5 (Compound 2b) is the inhibitor for Laccase with an IC₅₀ of 0.82 μM. Laccase-IN-5 increases the cell membrane permeability, limits the growth of hyphae, destorys the cell wall, and induces oxidative stress responses. Laccase-IN-5 exhibits antifungal activity against various plant pathogenic fungi and oomycetes, inhibits B. dothidea with an EC₅₀ of 0.96 mg/L .

HY-N16760

Wikstrol B	Microtubule/Tubulin HIV	Infection
Wikstrol B (compound 5) is a biflavonoid microtubule/tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC₅₀ value of 184 μM for microtubule polymerization and an EC₅₀ of 3.02 μM against HIV-1, acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal, antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7107

Fenchyl alcohol	Infection Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Environmental Pollutants Fungal
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-W782599

Senkyunolide B	Ligusticum striatum DC. Structural Classification Ketones, Aldehydes, Acids Apiaceae Plants Source Classification	Fungal PKC Calcineurin
Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes .

HY-N7107R

Fenchyl alcohol (Standard)	Structural Classification Other Monoterpenes other families Terpenoids Plants Source Classification	Reference Standards Fungal
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-N16760

Wikstrol B	Structural Classification Flavonoids Flavones Thymelaeaceae Phenols Plants Source Classification Wikstroemia indica	Microtubule/Tubulin HIV
Wikstrol B (compound 5) is a biflavonoid microtubule/tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC₅₀ value of 184 μM for microtubule polymerization and an EC₅₀ of 3.02 μM against HIV-1, acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal, antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica .

Cat. No.	Product Name	Chemical Structure

HY-B1858S

Isoprothiolane-d4
Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

Isoprothiolane-d4

Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

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