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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
hypoglycaemic
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "hypoglycaemic" in MCE Product Catalog:
2
Target:
Research Areas:
Acetohexamide is an orally active first-generation sulfonylurea agent used in research related to type 2 diabetes and cancer. Acetohexamide exerts reductase activity in human erythrocytes. Acetohexamide stimulates the pancreas to secrete insulin. Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas. Acetohexamide can inhibit the formation of circular chemorepellent induced defects (CCIDs) in lymphendothelial cell (LEC) monolayers. Acetohexamide inhibits markers of epithelial-to-mesenchymal-transition and migration. Acetohexamide suppresses the synthesis of 12(S)-HETE. Acetohexamide can potentiate hypoglycaemic action .
2
Category:
Alkaloids Piperidine Alkaloids Leguminosae Pyridine Alkaloids Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
Cat. No.: HY-17398
CAS No.: 145525-41-3
Synonyms: KAD-1229 anhydrous; S21403 anhydrous
Target:
Research Areas:
Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K + (KATP) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium can be used for the research of type 2 diabetes .
2
Target:
Research Areas:
Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes .
1
1
1 Cited Publications
Synonyms: DA-1229 tartrate
Target:
Research Areas:
Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation .
1
Category:
Natural Products Microorganisms Metabolic Disease Disease Research Fields Sweeteners Food Research
Target:
Cat. No.: HY-B1416A
CAS No.: 89197-00-2
Research Areas:
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease .
Cat. No.: HY-117985
CAS No.: 1222102-29-5
Synonyms: DA-1229
Target:
Research Areas:
Evogliptin (DA-1229) is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation .
Cat. No.: HY-B0682
CAS No.: 145375-43-5
Synonyms: KAD-1229 free acid anhydrous; S21403 free acid anhydrous
Target:
Research Areas:
Mitiglinide (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (KATP) channel antagonist. Mitiglinide is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide can be used for the research of type 2 diabetes .
Target:
Research Areas:
Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus .
Cat. No.: HY-77490AR
CAS No.: 107-88-0
Category:
Cat. No.: HY-U00211
CAS No.: 41177-35-9
Synonyms: NSC302998
Target:
Research Areas:
CS476 is a potent hypoglycaemic agent.
Cat. No.: HY-B1416AR
CAS No.: 89197-00-2
Research Areas:
Efaroxan (hydrochloride) (Standard) is the analytical standard of Efaroxan (hydrochloride). This product is intended for research and analytical applications. Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease .
Cat. No.: HY-17398R
CAS No.: 145525-41-3
Synonyms: KAD-1229 anhydrous (Standard); S21403 anhydrous (Standard)
Target:
Research Areas:
Mitiglinide (calcium) (Standard) is the analytical standard of Mitiglinide (calcium). This product is intended for research and analytical applications. Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium can be used for the research of type 2 diabetes .
Cat. No.: HY-B0682AR
CAS No.: 207844-01-7
Synonyms: KAD-1229 (Standard); S-21403 (Standard)
Target:
Research Areas:
Mitiglinide (calcium hydrate) (Standard) is the analytical standard of Mitiglinide (calcium hydrate). This product is intended for research and analytical applications. Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes .
Cat. No.: HY-W014078
CAS No.: 60875-16-3
Target:
Research Areas:
4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid has hypoglycaemic activity. 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid follows a mechanism based on the response to the oral glucose overcharge .
Category:
Alkaloids Piperidine Alkaloids Leguminosae Pyridine Alkaloids Plants Sophora flavescens Aiton
Target:
Cat. No.: HY-117985S
Synonyms: DA-1229-d9
Cat. No.: HY-N2840S
Synonyms: Allodulcitol-13C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
