14 Results for "

immunoconjugate

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "immunoconjugate" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P3239
CAS No.: 2050232-20-5
Synonyms: GSK2857916; Belantamab mafodotin-blm
Research Areas:  

Cancer

Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. The antibody portion is Belantamab (HY-P9980), and the drug-linker conjugate for ADC is McMMAF (HY-15578). Belantamab mafodotin has anti-myeloma activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-156035
CAS No.: 102650-30-6
Purity:  96.05%
Research Areas:  

Inflammation/Immunology

Bz-DTPA is a bifunctional chelator. Bz-DTPA can be used for preparing immunoconjugate of monoclonal antibody 2G3 labeled with indium-111 .
loading...
    loading...
Cat. No.: HY-78961
CAS No.: 55750-63-5
Synonyms: EMCS
Target:  

ADC Linkers

Research Areas:  

Cancer

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates .
loading...
    loading...
Cat. No.: HY-131974
CAS No.: 2166375-82-0
Purity:  99.80%
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41 .
loading...
    loading...
Cat. No.: HY-160441
CAS No.: 1629737-40-1
MC-Val-Cit-PAB-Ispinesib (Compound 509) is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker and Eg5 inhibitor. MC-Val-Cit-PAB-Ispinesib can be used for the synthesis of antibody-drug conjugates (ADCs) .
loading...
    loading...
Cat. No.: HY-138139A
CAS No.: 2490497-93-1
Purity:  99.46%
Synonyms: T785 hydrochloride
Research Areas:  

Inflammation/Immunology Cancer

AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist. AXC-715 can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants .
loading...
    loading...
Cat. No.: HY-D0892
CAS No.: 194357-64-7
Research Areas:  

Cancer

NSP-DMAE-NHS is an acridinium ester-based signal amplifier that can act as a luminescent probe to effectively improve the detection performance of biosensors. NSP-DMAE-NHS preserves the biochemical activity of biomolecules during the conjugation process. NSP-DMAE-NHS has been successfully applied to label mouse anti-human PI3 monoclonal antibodies for chemiluminescent immunoassays, as well as for pre-competitive chemiluminescent immunochromatographic detection of TP53 fusion proteins. NSP-DMAE-NHS can be used in detection studies of cancer and related biomarkers .
loading...
    loading...
Cat. No.: HY-P99492
CAS No.: 400010-39-1
Synonyms: SB-408075; huC242-DM1
Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative (DM1 (HY-19792)) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts .
loading...
    loading...
Cat. No.: HY-P99581
CAS No.: 1612758-88-9
Synonyms: OTSA101-DTPA; OTSA101-DTPA-90Y; OTSA101-SS01

Research Areas:  

Cancer

Tabituximab barzuxetan (exclude Y90) (OTSA101-DTPA; OTSA101-DTPA-90Y; OTSA101-SS01) is a immunoconjugate composed of a humanized monoclonal antibody targeting FZD-10 (OTSA-101). Tabituximab barzuxetan exhibits anti-tumor activity. Tabituximab barzuxetan can be used for the research of synovial sarcoma .
loading...
    loading...
Cat. No.: HY-138139B
CAS No.: 2479276-17-8
Purity:  99.76%
Synonyms: T785 trihydrochloride
Research Areas:  

Inflammation/Immunology Cancer

AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist. AXC-715 trihydrochloride can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants .
loading...
    loading...
Cat. No.: HY-P5413
CAS No.: 66839-66-5
Research Areas:  

Others

[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)
loading...
    loading...
Cat. No.: HY-148091
CAS No.: 1164275-01-7
Research Areas:  

Cancer

Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity .
loading...
    loading...
Cat. No.: HY-153212
CAS No.: 159857-65-5
Target:  

Drug Intermediate

Research Areas:  

Cancer

MC-Phe-Lys(MMT)-PABOH is a linker. MC-Phe-Lys(MMT)-PABOH can be used to synthesize the immunoconjugate BR96-Phe-Lys-PABC-DOX. MC-Phe-Lys(MMT)-PABOH can be used in the research of colorectal cancer and ovarian cancer .
loading...
    loading...
Cat. No.: HY-178885
(S)-4-(4-(2-(Methylamino)propyl)phenoxy)butanoic acid (TFA) (Compound H1) is a Methamphetamine hapten.(S)-4-(4-(2-(Methylamino)propyl)phenoxy)butanoic acid (TFA) can be coupled to the BSA, Keyhole limpet hemocyanin molecule. The immunoconjugate H1-KLH strongly induces an antibody response .
loading...
    loading...
  • 1