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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
liver PC
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "liver PC" in MCE Product Catalog:
Target:
Áreas de investigación:
Phosphatidylcholine transfer protein inhibitor-1 is a derivative of phosphatidylcholine transfer protein (PC-TP) inhibitor. Phosphatidylcholine transfer protein inhibitor-1 can be used for the research of obesity, type 2 diabetes, non-alcoholic fatty liver disease .
Referencia número: HY-N16066
No. CAS: 81474-59-1
Synonyms: CHNQD-0803
Category:
Target:
Referencia número: HY-157404
No. CAS: 2918764-16-4
Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive PIM-1 and PIM-2 kinase inhibitor with IC50s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines .
Referencia número: HY-178133
Pim-1 kinase-IN-14 is a PIM-1 kinase inhibitor with an IC50 value of 94 nM. Pim-1 kinase-IN-14 shows broad-spectrum and high-efficiency anticancer activity against multiple human cancer cell lines, including liver cancer (HepG-2), colon cancer (Caco-2), myeloid leukemia (NFS-60), and prostate cancer (PC-3) cells. Pim-1 kinase-IN-14exerts its anticancer effects by inducing apoptosis and activating caspase 3/7. Pim-1 kinase-IN-14 can be used for the study of cancers associated with PIM-1 kinase overexpression .
Target:
Áreas de investigación:
(±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.
Referencia número: HY-183589
Áreas de investigación:
Ferroptosis-IN-26 is a CEPT1-targeting ferroptosis inhibitor. Ferroptosis-IN-26 enhances CEPT1-dependent phosphatidylcholine remodeling to enrich cellular membranes with monounsaturated fatty acid-containing phosphatidylcholine (PC-MUFA). Ferroptosis-IN-26 suppresses lipid peroxidation. Ferroptosis-IN-26 can be used for the research of acute liver injury .
Referencia número: HY-184361
No. CAS: 143202-57-7
Synonyms: Ethyl 20:4BSO
Target:
Áreas de investigación:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Juniperonic acid ethyl ester (Ethyl 20:4BSO) is an orally active non-methylene-interrupted ω-3 polyunsaturated fatty acid ethyl ester. Juniperonic acid ethyl ester exists in Platycladus orientalis seed oil. Juniperonic acid ethyl ester reduces the ratio of 20:3n-9 to arachidonic acid in hepatic phosphatidylcholine of rats with essential fatty acid deficiency. Juniperonic acid ethyl ester is applicable to the research of hypertension and hepatic reperfusion injury .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
