19 Results for "

marine alkaloid

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "marine alkaloid" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-101848
CAS No.: 76343-94-7
Purity:  ≥98.0%
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .
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Cat. No.: HY-W001963
CAS No.: 634-97-9
Pyrrole-2-carboxylic acid is a natural alkaloid foumd in the marine bacterium Pelomonas puraquae sp. Nov. Pyrrole-2-carboxylic acid shows antibacterial activity and inhibits biofilm formation. Pyrrole-2-carboxylic acid serves as a precursor for various pyrrole derivatives like Clorobiocin (HY-123515), Coumermycin A1 (HY-N7452) in biosynthetic processes .
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Cat. No.: HY-N15451
CAS No.: 112515-42-1
Deoxytopsentin (compound 5) is a marine bisindole alkaloid and also a MRSA pyruvate kinase inhibitor. Deoxytopsentin exists in sponges. Deoxytopsentin exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus strains in vitro .
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Cat. No.: HY-N16411
CAS No.: 1392300-52-5
Carneamide A is a prenylated indole alkaloid produced by a marine-derived Aspergillus sp .
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Cat. No.: HY-130995
CAS No.: 247115-74-8
Agrochelin, an alkaloid cytotoxic antibiotic, is produced by the fermentation of a marine Agrobacterium sp. Agrochelin has cytotoxic activity in tumor cell lines .
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Cat. No.: HY-N12726
CAS No.: 2977255-36-8
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .
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Cat. No.: HY-142075
CAS No.: 14474-71-6
Antibacterial agent 134 is the major metabolite in the culture of Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp. NJ6-3-1. Antibacterial agent 134 can be used for bacterial infection .
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Cat. No.: HY-126601
CAS No.: 882403-69-2
Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x .
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Cat. No.: HY-116436
CAS No.: 135383-64-1
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance .
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Cat. No.: HY-125538
CAS No.: 34610-68-9
Purity:  99.2%
Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. .
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Cat. No.: HY-N6095
CAS No.: 1818218-33-5
Target:  

Endogenous Metabolite

Research Areas:  

Others

Nocarimidazole A is a white amorphous solid alkaloid with ultraviolet activity that can be isolated from marine actinomycete Nocardiopsis .
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Cat. No.: HY-116529
CAS No.: 115982-19-9
Lamellarin E is a biologically active marine alkaloid, while the Lamellarin series of alkaloids show potential cytotoxicity, topoisomerase I inhibition, protein kinase inhibition, multidrug resistance reversal, and anti-HIV-1 activity .
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Cat. No.: HY-N15283
CAS No.: 1141448-57-8
Baculiferins A is a DOPA-derived pyrrole alkaloid. Baculiferins A can be isolated from the Chinese marine sponge Iotrochota baculifera. Baculiferins A have anti-HIV activity .
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Cat. No.: HY-N6997
CAS No.: 634151-15-8
Ceratamine A is an antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp., acts as a microtubule-stabilizing agent. Ceratamine A exhibits cytotoxicity against human cancer cell lines .
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Cat. No.: HY-121014
CAS No.: 86047-14-5
Amphimedine is a polycyclic alkaloid isolated from the marine sponge Amphimedon sp. and belongs to the pyridoindole alkaloid class. Amphimedine has cytotoxic activity and has been studied as an anticancer metabolite along with neoamphimedine. Studies have shown that deoxyamphimedine damages DNA by generating reactive oxygen species, a mechanism different from that of amphimedine.
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Cat. No.: HY-N10256
CAS No.: 1623451-72-8
Varioxepine A is a 3H-oxepine-containing alkaloid with a new oxa-cage found in the marine algal-derived endophytic fungus Paecilomyces variotii. Varioxepine A inhibits plant pathogenic fungus Fusarium graminearum .
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Cat. No.: HY-W065835
CAS No.: 96562-96-8
2-Bromoaldisine is a pyrrole alkaloid that can be isolated from the Red Sea: marine sponge Stylissa carter. 2-Bromoaldisine inhibits HIV-1 vector infection. 2-Bromoaldisine inhibits Raf/MEK/MAPK pathway .
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Cat. No.: HY-N19134
CAS No.: 163136-25-2
Synonyms: (+)-Shearinine B
Shearinine B ((+)-Shearinine B) is an indole-diterpenoid alkaloid that can be found in the marine-derived fungus Penicillium janthinellum Biourge and Eupenicillium shearii. Shearinine B causes mortality in fall armyworm Spodoptera frugiperda and reduces growth rate of Helicoverpa zea larvae .
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Cat. No.: HY-183242
CAS No.: 120154-96-3
Target:  

Bacterial Parasite

Research Areas:  

Infection Neurological Disease Cancer

Eilatin is a seven-ring pyridoacridine marine alkaloid with anticancer, antibacterial, and antiparasitic activities. Eilatin acts as a DNA intercalator with selectivity for electron-deficient polycyclic purines; it can chelate Ni 2+ ions and cleave DNA via hydroxyl radical generation. Eilatin induces the SOS response in bacteria, inhibits cancer cell proliferation, and induces cancer cell differentiation and reversion of transformation. The IC50 of Eilatin against Trypanosoma brucei brucei is 1.33 μM. Eilatin can be used in research related to colon tumors, neuroblastoma, chronic myeloid leukemia, acute myeloid leukemia, and trypanosome infections .
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