22 Results for "

mast cell cytokine

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "mast cell cytokine" in MCE Product Catalog:

57
57 Publications Verification
Cat. No.: HY-123606
CAS No.: 1652629-23-6
GSK484 is a PAD4 inhibitor that effectively inhibits protein citrullination and the formation of neutrophil extracellular traps (NETs) by blocking the catalytic activity of PAD4. GSK484 suppresses the production of histone H3, MHC-I expression, CD8 + T cell activation, proliferation and inflammatory cytokine release. GSK484 reduces inflammation and bone destruction in collagen-induced rheumatoid arthritis, alleviates pain and mast cell activation in sickle cell disease, and improves myocardial ischemia-reperfusion injury and experimental colitis. In addition, GSK484 restores intestinal microbial homeostasis by reversing ferroptosis-induced dysbiosis. GSK484 can be used to study the disease mechanisms of rheumatoid arthritis, sickle cell disease, thrombosis, myocardial injury, colitis and other conditions .
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3
3 Cited Publications
Cat. No.: HY-12521
CAS No.: 1253186-49-0
Purity:  99.94%
Target:  

CRAC Channel

Research Areas:  

Inflammation/Immunology

GSK-5498A is a selective CARC channel inhibitor (IC50: 1 μM). GSK-5498A inhibits mediators release from mast cells and pro-inflammatory cytokines release from T cells. GSK-5498A can be used in the research of inflammatory disorders .
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1
1 Cited Publications
Cat. No.: HY-P7046
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Human
Source:  
CHO
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Cat. No.: HY-19393
CAS No.: 444659-43-2
SCH 351591 is a highly selective, orally active PDE4 inhibitor, with IC50 values of 58 nM and 153 nM in humans and rats, respectively. SCH 351591 effectively inhibits pathological processes such as cytokine production, eosinophilia, airway hyperresponsiveness and bronchospasm. SCH 351591 also induces microvascular injury, activates mast cells and endothelial cells, and causes increases in serum histamine and various inflammatory factors, leading to early vascular damage. SCH 351591 has been widely used in studies related to asthma, chronic obstructive pulmonary disease and drug-induced vascular injury .
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Cat. No.: HY-116474
CAS No.: 14484-44-7
Purity:  99.93%
Viridicatol is a quinolone alkaloid with anti-inflammatory, antibacterial, antifungal, osteogenic and chondrogenic activities. Viridicatol reduces the phosphorylation levels of ERK, JNK, p38 and STAT6; inhibits MMP-2, MMP-9, NF-κB signaling pathway and PTP1B; downregulates genes related to mast cell activation; and binds to SHN3 to activate the Wnt/SHN3 signaling pathway. Viridicatol inhibits the expression of pro-inflammatory mediators and cytokines, and promotes osteogenic/chondrogenic differentiation. Viridicatol can be used in studies related to fibrosarcoma, allergy, bacterial infection, fungal infection and osteoporosis .
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Cat. No.: HY-W015515
CAS No.: 7540-51-4
Synonyms: (S)-3,7-Dimethyloct-6-en-1-ol
L-Citronellol ((S)-3,7-Dimethyloct-6-en-1-ol) is a natural product with anti-allergic and neuroprotective effects. L-Citronellol inhibits mast cell activation and the release of inflammatory factors by inhibiting the ERK pathway. L-Citronellol inhibits BACE1/PSEN1 and AChE, reduces TNF-α expression and lipid peroxidation, demonstrating the potential of multi-target anti-Alzheimer's disease (AD) .
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Cat. No.: HY-114203
CAS No.: 88798-74-7
Synonyms: BE003
Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects .
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Cat. No.: HY-P991467

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

RG-7258 is a human monoclonal antibody (mAb) targeting CRLF2. RG-7258 blocks dendritic cell activation and mast cell cytokine release. RG-7258 reduces Th2 inflammation in a non-human primate model of allergic lung inflammation. RG-7258 can be used in asthma research .
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Cat. No.: HY-174607
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
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Cat. No.: HY-116474R
CAS No.: 14484-44-7
Viridicatol (Standard) is the analytical standard of Viridicatol (HY-116474). This product is intended for research and analytical applications. Viridicatol is a quinolone alkaloid with anti-inflammatory, antibacterial, antifungal, osteogenic and chondrogenic activities. Viridicatol reduces the phosphorylation levels of ERK, JNK, p38 and STAT6; inhibits MMP-2, MMP-9, NF-κB signaling pathway and PTP1B; downregulates genes related to mast cell activation; and binds to SHN3 to activate the Wnt/SHN3 signaling pathway. Viridicatol inhibits the expression of pro-inflammatory mediators and cytokines, and promotes osteogenic/chondrogenic differentiation. Viridicatol can be used in studies related to fibrosarcoma, allergy, bacterial infection, fungal infection and osteoporosis .
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Cat. No.: HY-P7083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Mouse
Source:  
CHO
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Cat. No.: HY-P70539
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73229
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Mouse
Source:  
Sf9 insect cells
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Cat. No.: HY-P73230
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Rat
Source:  
Sf9 insect cells
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Cat. No.: HY-P700134AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700218AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P73228
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P78319
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P701014
Purity:  ≥ 95%, as determined by Bis-Tris PAGE. ≥ 95% as determined by HPLC.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704399
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 cytokine; HP40; cytokine P40; P40
Species:  
Human
Source:  
HEK293
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