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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
modified DNA sequences
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "modified DNA sequences" in MCE Product Catalog:
1
1 Cited Publications
DMT-dC (ac) Phosphoramidite is a phosphoramidite used for incorporating N4-acetyl deoxycytidine into oligonucleotides. DMT-dC (ac) Phosphoramidite enables the synthesis of modified DNA sequences via standard solid-phase chemistry. DMT-dC (ac) Phosphoramidite is used in research on oligonucleotide synthesis .
製品番号: HY-160728
CAS 番号: 1048021-78-8
別名: 3′-O-Azidomethyl dATP
Target:
研究分野:
3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
製品番号: HY-160728A
別名: 3′-O-Azidomethyl dATP trisodium
Target:
研究分野:
3′-O-N3-dATP trisodium (3′-O-Azidomethyl dATP trisodium) is the trisodium salt form of 3′-O-N3-dATP. 3′-O-N3-dATP trisodium is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP trisodium acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
製品番号: HY-188030
CAS 番号: 106519-34-0
研究分野:
Biotin-14-dATP is a deoxyadenosine triphosphate analog modified by Biotin (HY-B0511), serving as a DNA labeling reagent that acts on E. coli DNA polymerase I. When incorporated into DNA probes, Biotin-14-dATP undergoes specific hybridization with complementary target DNA sequences, and its biotin group can bind to streptavidin-alkaline phosphatase conjugates, enabling colorimetric detection .
製品番号: HY-L005M
295 compounds
Epigenetics involves heritable phenotypic changes that occur without alterations to the underlying DNA sequence. Key mechanisms include DNA methylation, histone modifications, and regulation by small non-coding RNAs such as microRNAs. By modifying DNA, histones, or RNA—while leaving their primary sequences intact—these processes influence molecular function and regulation, thereby playing critical roles in cellular differentiation, embryonic development, gene expression control, aging, and diseases such as cancer.
MCE provide a unique collection of 295 epigenetics-related compounds. For each regulatory target and its subtype, 3 to 5 highly specific representative compounds have been retained, which can be used in epigenetic and related disease research.
製品番号: HY-185423
PreQ1-DBCO is a strained cyclooctyne commonly used in click chemistry. PreQ1-DBCO undergoes TGT-catalyzed guanine base exchange in DNA oligonucleotide stem-loops to replace guanine. PreQ1-DBCO functionalizes custom DNA oligonucleotide sequences. DBCO-modified DNA oligonucleotides are conjugated with azide peptides via strain-promoted azide-alkyne click chemistry (SPAAC). PreQ1-DBCO can be used in studies of hemophilia B (Christmas disease) .
製品番号: HY-P11686
CAS 番号: 1052677-90-3
Target:
研究分野:
製品番号: HY-138586S
Target:
Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphoramidites
研究分野:
DMT-dC(ac) Phosphoramidite- 13C9, 15N3 is the 13C, 15N-labeled DMT-dC(ac) Phosphoramidite (HY-138586). DMT-dC (ac) Phosphoramidite is a phosphoramidite used for incorporating N4-acetyl deoxycytidine into oligonucleotides. DMT-dC (ac) Phosphoramidite enables the synthesis of modified DNA sequences via standard solid-phase chemistry. DMT-dC (ac) Phosphoramidite is used in research on oligonucleotide synthesis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
