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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
neurotransmitter amines
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "neurotransmitter amines" in MCE Product Catalog:
6
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
Cat. No.: HY-B2132S1
CAS No.: 340257-60-5
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NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.
Synonyms: 3-(2-Aminoethyl)indole~2-(3-Indolyl)ethylamine (Standard)
Target:
Cat. No.: HY-B1018AS
CAS No.: 1219798-40-9
Cat. No.: HY-B2132S
CAS No.: 362049-48-7
Cat. No.: HY-16731
CAS No.: 676479-06-4
Synonyms: EVT 302; RG1577; RO4602522
Research Areas:
Sembragiline (EVT 302) is a potent, selective and reversible monoamine oxidase B (MAO-B) inhibitor. Sembragiline reduces the metabolism of dopamine and other amine neurotransmitters by inhibiting the activity of the MAO-B enzyme, thereby potentially increasing the concentration of these neurotransmitters in the brain. Inhibition of the MAO-B enzyme also reduces the formation of toxic reactive oxygen species (ROS) that play a role in the pathological process of AD. Sembragiline has good oral activity and blood-brain barrier permeability. Sembragiline can be used in studies of AD, especially in patients with AD who show increased MAO-B activity .
Cat. No.: HY-E70519B
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Research Areas:
Tyramine oxidase, Arthrobacter sp. (EC 1.4.3.6) is a class of enzymes that catalyze the oxidation of various biogenic amines, including many neurotransmitters, histamine, and exogenous amines. Tyramine oxidase, Arthrobacter sp. (EC 1.4.3.6) catalyzes the oxidation of primary amines to aldehydes, releasing ammonia and hydrogen peroxide. Each subunit of this reaction requires a copper ion, with topiramate as a cofactor.
Cat. No.: HY-101540R
CAS No.: 129024-87-9
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NMI 8739 (Standard) is the analytical standard of NMI 8739 (HY-101540). This product is intended for research and analytical applications. NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.
Cat. No.: HY-186306
CAS No.: 1898180-94-3
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Research Areas:
MAO-A-IN-5 (compound 4g) is a selective human monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.250 μM against MAO-A. MAO-A-IN-5 competitively inhibits the activity of MAO enzymes, impedes the metabolism of neurotransmitter amines, and potentially reduces hydrogen peroxide produced by the MAO-catalyzed cycle. MAO-A-IN-5 can be used for research on Parkinson's disease and depression .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
