83 Results for "

p19

" in MedChemExpress (MCE) Product Catalog:
Products (83)

83 Results for "p19" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1494
CAS No.: 57468-17-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
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1
1 Cited Publications
Cat. No.: HY-P73195
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23A; Interleukin 23, Alpha Subunit p19; Interleukin 23 Subunit Alpha; Interleukin-23 Subunit Alpha; SGRF; Interleukin-23 Subunit p19; IL23p19; IL-23 Subunit Alpha; IL-23A; IL-23p19; IL-23; IL-23-A; p19; JKA3 Induced Upon T-Cell Activation; Interleukin-S
Species:  
Rat
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P74816
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23A; Interleukin 23, Alpha Subunit p19; Interleukin 23 Subunit Alpha; Interleukin-23 Subunit Alpha; SGRF; Interleukin-23 Subunit p19; IL23p19; IL-23 Subunit Alpha; IL-23A; IL-23p19; IL-23; IL-23-A; p19; JKA3 Induced Upon T-Cell Activation; Interleukin-S
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P80615
Synonyms: CDK4 inhibitor p16 INK4 antibody; CDK4I antibody; CDKN2 antibody; CDKN2A antibody; Cell cycle negative regulator beta antibody; CMM2 antibody; Cyclin dependent kinase 4 inhibitor A antibody; Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody; Cyclin Dependent Kinase Inhibitor 2A antibody; Cyclin dependent kinase inhibitor 2A isoform 4 antibody; Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody; Cyclin dependent kinase inhibitor p16 antibody; INK4 antibody; INK4A antibody; MLM antibody; MTS1 antibody; Multiple tumor suppressor 1 antibody; p14 antibody; p16 antibody; P16INK4 antibody; p16INK4a antibody; p19 antibody; p19Arf antibody; TP16 antibody;

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P72785
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4); Prev. CDKN2; Multiple Tumor Suppressor 1; Prev. MLM; CDKN2A/ARF Intron 2 LncRNA; P14ARF; Alternative Reading Frame; CDK4I; Inhibitor Of Cdk4 A; MTS1; MTS-1; P16; Truncated Tumor
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P99248
CAS No.: 1612838-76-2
Synonyms: Risankizumab rzaa; BI 655066; ABBV-066

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting IL-23 p19 subunit (Kd <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC50 = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .
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Cat. No.: HY-P9931
CAS No.: 1350289-85-8
Synonyms: CNTO 1959

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research .
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Cat. No.: HY-P990217

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived anti-mouse IL-23 p19 IgG1 monoclonal antibody. Anti-Mouse IL-23 p19 Antibody (G23-8) alleviates inflammation by restoring CLDN8 expression. Anti-Mouse IL-23 p19 Antibody (G23-8) can be used for research on inflammation conditions such as colitis and asthma .
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Cat. No.: HY-P99737
CAS No.: 1884201-71-1
Synonyms: LY­3074828

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .
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Cat. No.: HY-P99256
CAS No.: 1326244-10-3
Synonyms: SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Tildrakizumab (SCH 900222) is a humanized anti-IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 (Kd: 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis .
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Cat. No.: HY-P99485
CAS No.: 1610353-18-8
Synonyms: AMG 139; MEDI2070

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a KD of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .
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Cat. No.: HY-P990057
CAS No.: 2622900-74-5
Synonyms: IBI-112

Target:  

Interleukin Related

Research Areas:  

Cancer

Picankibart is a human-derived IgG1κ antibody targeting IL23A. Picankibart specifically binds to the IL23 p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.
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Cat. No.: HY-108440
CAS No.: 326886-05-9
Purity:  99.88%
Target:  

Myosin

Research Areas:  

Cardiovascular Disease

Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
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Cat. No.: HY-P991277
Synonyms: HS-20137

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .
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Cat. No.: HY-P991274

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

BMS-986010 is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). BMS-986010 reduces IL-23-induced STAT3 phosphorylation and inhibits Th17 cell differentiation and the release of proinflammatory cytokines (such as IL-17 and TNF-α). BMS-986010 is promising for research of autoimmune diseases such as psoriasis and Crohn's disease .
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Cat. No.: HY-RS11818
Research Areas:  

Others

REG1A Human Pre-designed siRNA Set A contains three designed siRNAs for REG1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-147934
CAS No.: 2432825-93-7
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines .
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Cat. No.: HY-P11198
Research Areas:  

Cancer

AC-P19M is an anticancer peptide. AC-P19M induces apoptosis by disrupting the cell membrane of cancer cells. AC-P19M reverses epithelial-mesenchymal transition (EMT). AC-P19M shows anti-angiogenic activity through the inhibition of VEGF-VEGFR2/ERK/Akt signaling. AC-P19M can be used for lung cancer research .
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Cat. No.: HY-P78152
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL23A; Interleukin 23, Alpha Subunit p19; Interleukin 23 Subunit Alpha; Interleukin-23 Subunit Alpha; SGRF; Interleukin-23 Subunit p19; IL23p19; IL-23 Subunit Alpha; IL-23A; IL-23p19; IL-23; IL-23-A; p19; JKA3 Induced Upon T-Cell Activation; Interleukin-S
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-RS06740
Research Areas:  

Others

Il23a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il23a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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